IP Library Granted Patent US 8,699,771
Granted Patent B2
US 8,699,771 · App. 12/622,006 · Granted Apr 15, 2014

Method and apparatus for reducing motion-related imaging artifacts

Inventors: Scott David Wollenweber (Waukesha, WI); Alexander Ganin (Whitefish Bay, WI); Kris Filip Johan Jules Thielemans (Putney, GB); Larry Pierce (Seattle, WA); Adam Alessio (Seattle, WA); Paul Kinahan (Seattle, WA); Chi Liu (Seattle, WA)
Assignee: General Electric Company
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Quick Facts
Patent No.
US 8,699,771
App. No.
12/622,006
Granted
Apr 15, 2014
Kind
B2
Abstract

A method and apparatus are provided for reducing motion related imaging artifacts. The method includes obtaining an image data set of a region of interest in an object, obtaining a motion signal indicative of motion of the region of interest, determining at least one quiescent period of at least a portion of the motion signal, extracting image data from the image data set that is within the determined quiescent period to form an image data subset, and generating an image of the region of interest using the image data subset.

Claims (39)

1. A method for reducing motion related imaging artifacts, said method comprising:

obtaining a first image data set of a region of interest in an object;

obtaining a computed tomography (CT) image data set;

obtaining, using the first image data set, a motion signal indicative of motion of the region of interest;

extracting a displacement histogram of the motion signal;

assigning a weighting factor, based upon the displacement histogram, to a plurality of CT images of the CT image data set to provide weighted CT images; and

averaging and normalizing the weighted CT images to form a quiescent CT image.

2. A method in accordance with claim 1 wherein obtaining the first image data set further comprises obtaining at least one of a Positron Emission Tomography (PET) emission data set and a Single Photon Emission Computed Tomography (SPECT) emission data set.

3. A method in accordance with claim 1 further comprising identifying a window in the displacement histogram using a peak fraction of the first image data set.

4. A method in accordance with claim 1 further comprising identifying a window in the displacement histogram using a counts fraction of the first image data set.

5. A method in accordance with claim 1 further comprising identifying a window in the displacement histogram using a signal-to-noise ratio of the first image data set.

6. A method in accordance with claim 1 further comprising:

matching the quiescent CT image with a positron emission tomography (PET) image to improve attenuation correction and PET localization.

7. A method in accordance with claim 1 further comprising applying a baseline correction to the motion signal to compensate for baseline shift.

8. A method in accordance with claim 1 , further comprising using a function based on an end of expiration to generate a baseline compensated motion signal from the motion signal.

9. A method in accordance with claim 1 , further comprising disregarding inspiration phase data.

10. A multi-modality imaging system comprising a first modality unit, a second modality unit, and a quiescent period gating module operationally coupled to the first and second modality units, wherein the quiescent period gating module is programmed to:

obtain, based on a first image data set obtained using the first modality unit, a motion signal indicative of motion of a region of interest;

obtain a computed tomography (CT) image data set using the second modality unit;

extract a displacement histogram of the motion signal;

assign a weighting factor, based upon the displacement histogram, to a plurality of images of the CT image data set to provide weighted CT images; and

average and normalize the weighted CT images to form a quiescent CT image.

11. A multi-modality imaging system in accordance with claim 10 , wherein the first modality unit comprises at least one of a Positron Emission Tomography (PET) system and a Single Photon Emission Computed Tomography (SPECT) imaging system.

12. A multi-modality imaging system in accordance with claim 10 , wherein the quiescent period gating module is further programmed to identify a window in the displacement histogram using at least one of a peak fraction method, a counts fraction method, and a signal-to-noise ratio method.

13. A multi-modality imaging system in accordance with claim 10 , wherein the quiescent period gating module is further programmed to apply a baseline correction to the motion signal to compensate for baseline shift.

14. A multi-modality imaging system in accordance with claim 10 , wherein the quiescent period gating module is further programmed to use a function based on an end of expiration to generate a baseline compensated motion signal from the motion signal.

15. A multi-modality imaging system in accordance with claim 10 , wherein the quiescent period gating module is further programmed to disregard inspiration phase data.

16. A tangible and non-transitory computer readable medium encoded with a program to instruct a computer to:

obtain a first image data set of a region of interest in an object from a PET imaging system;

obtain a computed tomography (CT) image data set;

obtain a motion signal indicative of motion of the region of interest using the first image data set;

extract a displacement histogram of the motion signal;

assign a weighting factor, based upon the displacement histogram, to a plurality of CT images of the CT image data set to provide weighted CT images;

average and normalize the weighted CT images to form a quiescent CT image.

17. A computer readable medium in accordance with claim 16 wherein the program is programmed to further instruct the computer to:

identify a window in the displacement histogram using at least one of a peak fraction method, a counts fraction method, and a signal-to-noise ratio method; and

reconstruct an image of the object of interest using image data identified within the window.

18. A tangible and non-transitory computer readable medium in accordance with claim 16 wherein the program is programmed to further instruct the computer to use a function based on an end of expiration to generate a baseline compensated motion signal from the motion signal.

19. A tangible and non-transitory computer readable medium in accordance with claim 16 wherein the program is programmed to further instruct the computer to disregard inspiration phase data.

Assignments (3)
CONFIRMATORY LICENSE Recorded Oct 7, 2016
From: UNIVERSITY OF WASHINGTON
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 040289/0360 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 6, 2014
From: KINAHAN, PAUL; ALLESSIO, ADAM; LIU, CHI; PIERCE, LARRY
To: UNIVERSITY OF WASHINGTON CENTER FOR COMMERCIALIZATION
Reel/Frame 032833/0721 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 19, 2011
From: WOLLENWEBER, SCOTT DAVID; GANIN, ALEXANDER; THIELEMANS, KRIS JOHAN JULES
To: GENERAL ELECTRIC COMPANY
Reel/Frame 025663/0453 →
Continuity (1)
Related Publication 20110116695A1 · May 19, 2011