Immunoassay reagent composition
In one embodiment, the invention is to a dry reagent composition configured as a solute to be dissolved into whole-blood prior to a whole-blood immunoassay, the dry reagent composition comprising: goat IgG, mouse IgG, dextran, a buffer, proclin, and sodium chloride in a support matrix. In another embodiment, the invention is to a dry reagent composition configured as a solute to be dissolved into whole-blood prior to a whole-blood immunoassay, the dry reagent composition comprising dextran and a salt in a support matrix.
1. A dry reagent composition configured as a solute to be dissolved into whole-blood prior to a whole-blood immunoassay, the dry reagent composition comprising: goat IgG, mouse IgG, dextran, a buffer, a reagent stabilizer, and a salt in a support matrix comprising cellulose, polyvinyl alcohol, gelatin, or mixtures thereof; wherein the dry reagent composition is in dry form as a coating.
2. The dry reagent composition of claim 1 , wherein the dry reagent composition further comprises sodium azide.
3. The dry reagent composition of claim 1 , wherein the salt is NaCl, KCl, MgCl2, CaCl2, LiCl, NaNO3, Na2SO4, or mixtures thereof.
4. The dry reagent composition of claim 1 , wherein the salt is a buffer salt comprising Tris, 2-(N-morpholino)ethanesulfonic acid (MES), phosphate, or 4-(2-hydroxyethyl)-I-piperazineethanesulfonic acid (HEPES).
5. The dry reagent composition of claim 1 , wherein the reagent stabilizer comprises lactitol.
6. The dry reagent composition of claim 1 , wherein the dry reagent composition further comprises heparin.
7. The dry reagent composition of claim 1 , wherein the buffer is 2-(N-morpholino)ethanesulfonic acid (MES), phosphate, or 4-(2-hydroxyethyl)-I-piperazineethanesulfonic acid (HEPES).
8. The dry reagent composition of claim 1 , wherein the buffer is Tris.