Granted Patent
B2
US 8,815,947 · App. 13/540,775 · Granted Aug 26, 2014
Methods of treating metabolic disorders
Assignee:
Case Western Reserve University
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Abstract
A method of increasing the insulin sensitivity of insulin resistant cells includes administering to the cells an amount of all-trans-retinoic acid effective to activate transcription factor perosixome proliferator-activated receptor (PPAR) β/δ of the cells.
Claims (2)
1. A method of suppressing adiposity in a subject that consumes a high fat or high caloric diet, the method comprising administering to the subject an amount of all-trans-retinoic acid effective to increase insulin consisting of insulin resistant cells in the subject.
2. The method of claim 1 , the all-trans-retinoic acid being administered at an amount effective to effective to activate transcription factor PPAR β/δ of the insulin resistant cells.
Assignments (1)
CONFIRMATORY LICENSE
Recorded Jan 27, 2017
From: CASE WESTERN RESERVE UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 041538/0422 →
Continuity (3)
Provisional Application
60938578
· May 17, 2007