Bi-Layer Pressed Powders Oral Adhering Tablet with Acacia gum adhesive
A bi-layer, oral adhering tablet (troche) made by pressing powders with a bi-layer tablet press, having greater than 80% acacia gum as an adhesive in an adhering layer. In a preferred embodiment, the tablet has about 99% acacia gum.
1. A bi-layer, pressed powders, oral adhering tablet, comprising:
a first layer comprising an adhesive powder, wherein the adhesive powder comprises at least 80% acacia gum; and
a second layer comprising a powder containing an ingredient to be released into saliva in a mouth;
wherein dissolution time of the tablet in the mouth is at least 25 minutes, and wherein the tablet is at least 5 mm in two dimensions;
wherein the side of the tablet opposite the adhesive is either planar or rounded or substantially flat in a center area.
2. The tablet of claim 1 , wherein the adhesive powder comprises about 99% acacia gum.
3. The tablet of claim 1 wherein the volume of the second layer is greater than the volume of the first layer.
4. The tablet of claim 1 , wherein the tablet is substantially flat on an adhesive side and rounded on the opposite side.
5. The tablet of claim 1 , wherein the ingredient comprises one or more polyols.
6. The tablet of claim 5 , wherein at least one of the polyols is xylitol.
7. The tablet of claim 6 , wherein the xylitol is present at a concentration of at least 75% in the second layer.
8. The tablet of claim 6 , wherein the xylitol is present at a concentration of at least 90% in the second layer.
9. The tablet of claim 5 , wherein the at least one polyol is present at a concentration of at least 90% in the second layer.
10. The tablet of claim 1 , wherein the first layer is about 0.5 mm thick.
11. The tablet of claim 1 , wherein the tablet is about 12 mm in diameter.
12. The tablet of claim 5 , wherein the polyol comprises grains of powder.