IP Library › Granted Patent US 8,912,355
Granted Patent B2
US 8,912,355 · App. 12/892,671 · Granted Dec 16, 2014

Linoleic phospholipids and uses thereof for inhibiting inflammatory and neurodegenerative processes

Inventors: Nihar Pandey (Ottawa, CA); Daniel Sparks (Gatineau, CA)
Assignee: University of Ottawa Heart Institute
C07F9/10A61K31/661
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Quick Facts
Patent No.
US 8,912,355
App. No.
12/892,671
Granted
Dec 16, 2014
Kind
B2
Abstract

Described herein are compositions of an linoleic phospholipid for inhibiting inflammatory pathways or neurodegenerative processes. Also provided are uses of such compositions and methods of inhibiting inflammatory or neurodegenerative processes by administering a composition that includes an linoleic phospholipid and optionally a carrier to a cell, cell culture or subject in need of such treatment.

Claims (4)

1. A method of inhibiting an accumulation of amyloid proteins, tau proteins or both proteins in neuronal cells comprising treating said neuronal cells with a composition comprising a linoleic phospholipid.

2. The method of claim 1 , wherein the linoleic phospholipid is dilinoleoylphosphatidylcholine.

3. The method of claim 1 , wherein the accumulation of amyloid protein is inhibited.

4. The method of claim 1 , wherein the accumulation of tau protein is inhibited.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 16, 2010
From: PANDEY, NIHAR; SPARKS, DANIEL
To: UNIVERSITY OF OTTAWA HEART INSTITUTE
Reel/Frame 025378/0453 →
Continuity (2)
Provisional Application 61246775 · Sep 29, 2009
Related Publication 20110077224A1 · Mar 31, 2011