Targeted delivery of magnetically tagged active agents in combination with negative pressure wound therapy
Methods and systems for treating a wound using targeted delivery of magnetically-tagged active agents in combination with negative pressure wound therapy are presented. In particular, a magnetically-active wound insert may be used to attract magnetically-tagged stem cells to a wound site to treat the wound.
1. A wound-treatment method comprising:
obtaining a wound dressing comprising:
a drape adapted to be coupled to the skin adjacent a wound of a patient such that the drape covers the wound and forms a space between the drape and the wound; and
a wound insert disposed within the space; wherein the wound dressing is configured to be coupled to a negative pressure source;
introducing a magnetically-tagged therapeutic agent into the body of the patient; and
applying negative pressure to the wound dressing using the negative pressure source.
2. The method of claim 1 , where the magnetically-tagged therapeutic agent is configured to be introduced into the body of the patient via a conduit coupled to the wound dressing.
3. The method of claim 1 , where the wound insert further comprises a magnetic material.
4. The method of claim 1 , further comprising releasing negative pressure from the wound dressing.
5. The method of claim 1 , further comprising reapplying negative pressure to remove accumulated fluid from the wound site.
6. The method of claim 1 , further comprising modulating the negative pressure on the wound dressing.
7. The method of claim 1 , further comprising modulating the density of the wound insert.
8. The method of claim 1 , where the wound dressing further comprises an electromagnet configured to be coupled to a voltage source.
9. The method of claim 8 , further comprising modulating the strength of the magnetic field generated by the electromagnet.
10. The method of claim 1 , further comprising coupling an electromagnet to the drape adjacent and external to the wound.
11. The method of claim 1 , further comprising holding a magnet sufficiently close to the wound that the magnetically-tagged therapeutic agent is drawn toward the wound.