IP Library › Granted Patent US 8,969,573
Granted Patent B2
US 8,969,573 · App. 13/807,132 · Granted Mar 3, 2015

Compounds for the inhibition of cellular proliferation

Inventors: Michael Chorev (Chestnut Hill, MA); Bertal Huseyin Aktas (Newton, MA); Jose A. Halperin (Brookline, MA); Gerhard Wagner (Chestnut Hill, MA)
Assignee: President and Fellows of Harvard College
C07D277/84C07D233/88C07D263/48C07D277/50C07D417/04C07D417/10C07D417/12C07D277/30C07D277/42C07D513/04
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Quick Facts
Patent No.
US 8,969,573
App. No.
13/807,132
Granted
Mar 3, 2015
Kind
B2
Abstract

Compositions and methods for inhibiting translation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, (4) disorders associated with viral infections, and/or (5) non-proliferative metabolic disorders such as type II diabetes where inhibition of translation initiation is beneficial using the compounds disclosed herein.

Claims (1)

1. A compound having the structure

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 5, 2013
From: AKTAS, HUSEYIN; CHOREV, MICHAEL; HALPERIN, JOSE A.; WAGNER, GERHARD
To: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Reel/Frame 030741/0636 →
CONFIRMATORY LICENSE Recorded Jan 14, 2013
From: HARVARD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 029622/0007 →
Continuity (2)
Provisional Application 61359227 · Jun 28, 2010
Related Publication 20130178505A1 · Jul 11, 2013