IP Library › Granted Patent US 8,975,278
Granted Patent B2
US 8,975,278 · App. 11/901,941 · Granted Mar 10, 2015

8-hydroxy quinoline derivatives

Inventors: Kevin Jeffrey Barnham (Coburg, AU); Elisabeth Colette Louise Gautier (Bentleigh, AU); Gaik Beng Kok (North Carlton, AU); Guy Krippner (Glen Waverley, AU)
Assignee: Prana Biotechnology Limited
A61K31/47A61K31/4709A61K31/4725A61K45/06C07D215/26C07D215/38C07D215/48C07D401/04C07D401/12C07D401/14C07D409/04C07D417/12C07D417/14
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Quick Facts
Patent No.
US 8,975,278
App. No.
11/901,941
Granted
Mar 10, 2015
Kind
B2
Abstract

The present invention describes a method for the treatment of a neurological condition in a subject which comprises administering to a subject in need thereof a therapeutically effect amount of a compound of the formula or pharmaceutically acceptable salts, hydrates, or solvates thereof.

Claims (5)

1. A method for the treatment of Alzheimer's disease in a subject which comprises administering to the subject in need thereof a therapeutically effective amount of

or a pharmaceutically acceptable salt thereof.

2. The method of claim 1 , in which the compound is administered in association with a pharmaceutically acceptable carrier.

3. The method of claim 1 , in which the compound is administered in association with a medicament, said medicament being an inhibitor of the acetyl cholinesterase active site, an antioxidant, an anti-inflammatory agent or an oestrogenic agent.

4. The method of claim 1 , in which the compound is in hydrate form.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 4, 2008
From: BARNHAM, KEVIN JEFFREY; GAUTIER, ELISABETH COLETTE LOUISE; KOK, GAIK BENG; KRIPPNER, GUY
To: PRANA BIOTECHNOLOGY LIMITED
Reel/Frame 020595/0779 →
Priority Claims (1)
AU 2002950217 · Jul 16, 2002 · national
Continuity (2)
Continuation In Part 10521902
Related Publication 20080161353A1 · Jul 3, 2008