IP Library Granted Patent US 8,980,950
Granted Patent B2
US 8,980,950 · App. 14/069,447 · Granted Mar 17, 2015

Calcilytic compounds

Inventors: Robert W. Marquis (Collegeville, PA); Linda N. Casillas (Collegeville, PA); Joshi M. Ramanjulu (Collegeville, PA); James Francis Callahan (King of Prussia, PA)
Assignee: GlaxoSmithKline, LLC
C07C229/34C07C217/30C07C217/32C07C217/34C07C217/54C07C2102/08
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 8,980,950
App. No.
14/069,447
Granted
Mar 17, 2015
Kind
B2
Abstract

Novel calcilytic compounds and methods of using them are provided.

Claims (3)

1. A method of treating osteoarthritis, which comprises the administration to a subject in need of treatment thereof an effective amount of 3-{3,4-difluoro-5-[(R)-2-hydroxy-3-(2-indan-2-yl-1,1-dimethyl-ethylamino)-propoxy]-phenyl}propionic acid.

2. A method of treating osteoarthritis, which comprises the administration to a subject in need of treatment thereof an effective amount of a pharmaceutically acceptable salt of 3-{3,4-difluoro-5-[(R)-2-hydroxy-3-(2-indan-2-yl-1,1-dimethyl-ethylamino)-propoxy]-phenyl}-propionic acid.

3. A method of treating osteoarthritis, which comprises the administration to a subject in need of treatment thereof an effective amount of 3-{3,4-difluoro-5-[(R)-2-hydroxy-3-(2-indan-2-yl-1,1-dimethyl-ethylamino)-propoxy]-phenyl}-propionic acid hydrochloride.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE US APPLICATION NUMBER WAS INCORRECTED RECORDED PREVIOUSLY RECORDED ON REEL 032411 FRAME 0914. ASSIGNOR(S) HEREBY CONFIRMS THE THE APPLICATION NUMBER WAS ERRONEOUSLY RECORDED AS: 14/063447; THE CORRECT APPLICATION NUMBER IS: 14/069447. Recorded Mar 19, 2014
From: MARQUIS, ROBERT W.; CASILLAS, LINDA N.; RAMANJULU, JOSHI M.; CALLAHAN, JAMES FRANCIS
To: SMITHKLINE BEECHAM CORPORATION
Reel/Frame 032474/0197 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2014
From: MARQUIS, ROBERT W.; CASILLAS, LINDA N.; RAMANJULU, JOSHI M.; CALLAHAN, JAMES FRANCIS
To: SMITHKLINE BEECHAM CORPORATION
Reel/Frame 032411/0914 →
CHANGE OF NAME Recorded Mar 12, 2014
From: SMITHKLINE BEECHAM CORPORATION
To: GLAXOSMITHKLINE LLC
Reel/Frame 032429/0940 →
Continuity (6)
Continuation 13764126 · Feb 11, 2013
Continuation 12894644 · Sep 30, 2010
Continuation 12393284 · Feb 26, 2009
Division 10536416
Provisional Application 60429105 · Nov 26, 2002
Related Publication 20140057980A1 · Feb 27, 2014