IP Library Granted Patent US 8,981,126
Granted Patent B2
US 8,981,126 · App. 14/000,997 · Granted Mar 17, 2015

Cyclopropenylidene-stabilized phosphenium cations

Inventors: Manuel Alcarazo (Mülheim an der Ruhr, DE); Hans Bruns (Duisburg, DE); Jekaterina Petuskova (Riga, LV)
Assignee: Studiengesellshaft Kohle mbH
C07F9/5018C07F9/5022C07F15/0073C07F15/0093C07F1/12B01J31/2404C07D311/94
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Quick Facts
Patent No.
US 8,981,126
App. No.
14/000,997
Granted
Mar 17, 2015
Kind
B2
Abstract

Phosphenium compounds with the general formula I: in which R 1 , R 2 , R 3 and R 4 are identical or different and represent a linear or branched C 1 -C 6 -alkyl radical, which can optionally be substituted, or R 1 and R 2 and/or R 3 and R 4 are bonded to one another with the formation of a ring, R 5 and R 6 stand for a saturated or unsaturated and linear or branched alkyl group, alkenyl group or aryl group, which can have suitable substituents, even heteroatoms as substituents, or a heteroatom-comprising hydrocarbon group, which can have suitable substituents, and the R 5 and R 6 radicals can form a ring which can be 4- to 20-membered, saturated or unsaturated and alicyclic or heteroalicyclic and can exhibit suitable substituents, X − represents an anion, a process for the preparation thereof, and also the use of these compounds in metal complexes which can be used as catalysts in organic synthesis, are claimed.

Claims (31)

1. A phosphenium compound with the general formula I:

in which R 1 , R 2 , R 3 and R 4 are identical or different and represent a linear or branched C 1 -C 6 -alkyl radical, which can optionally be substituted, or R 1 and R 2 and/or R 3 and R 4 are bonded to one another with the formation of a ring,

R 5 and R 6 stand for a saturated or unsaturated and linear or branched alkyl group, alkenyl group or aryl group, which can have suitable substituents, or a heteroatom-comprising hydrocarbon group, which can have suitable substituents, and the R 5 and R 6 radicals can form a ring which can be 4- to 20-membered, saturated or unsaturated and alicyclic or heteroalicyclic and can exhibit suitable substituents, and

X − represents an anion chosen from BF 4 − , PF 6 − , SbF 6 − and/or BPh 4 − .

2. The phosphenium compound as claimed in claim 1 , wherein R 1 , R 2 , R 3 and R 4 , each independently of one another, are chosen from isopropyl and tert-butyl.

3. A process for the preparation of the phosphenium compound with the general formula I as claimed in claim 1 , said process comprising: reacting the halocyclopropenium salt with the general formula II:

in which R 1 , R 2 , R 3 and R 4 are defined in claim 1 and Y represents a halogen atom, with a phosphine of the general formula III:

HPR 5 R 6   III

in which R 5 and R 6 are defined as in claim 1 .

4. The process as claimed in claim 3 , wherein Y represents chlorine.

5. A metal complex comprising as a ligand a phosphenium compound of the general formula I:

in which R 1 , R 2 , R 3 and R 4 are identical or different and represent a linear or branched C 1 -C 6 -alkyl radical, which can optionally be substituted, or R 1 and R 2 and/or R 3 and R 4 are bonded to one another with the formation of a ring,

R 5 and R 6 stand for a saturated or unsaturated and linear or branched alkyl group, alkenyl group or aryl group, which can have suitable substituents, or a heteroatom-comprising hydrocarbon group, which can have suitable substituents, and the R 5 and R 6 radicals can form a ring which can be 4- to 20-membered, saturated or unsaturated and alicyclic or heteroalicyclic and can exhibit suitable substituents, and

X − represents an anion.

6. A metal complex as claimed in claim 5 , having the general formula IV:

in which R 1 , R 2 , R 3 and R 4 are identical or different and represent a linear or branched C 1 -C 6 -alkyl radical, which can optionally be substituted, or R 1 and R 2 and/or R 3 and R 4 are bonded to one another with the formation of a ring,

R 5 and R 6 stand for a saturated or unsaturated and linear or branched alkyl group, alkenyl group or aryl group, which can have suitable substituents, or a heteroatom-comprising hydrocarbon group, which can have suitable substituents, and the R 5 and R 6 radicals can form a ring which can be 4- to 20-membered, saturated or unsaturated and alicyclic or heteroalicyclic and can exhibit suitable substituents,

X − represents an anion,

M represents a metal atom chosen from the group consisting of B, Cu, Ag, Au, Ru, Rh, Pd, Os, Ir and Pt,

L represents n identical or different ligands and n represents a number from 1 to 3.

7. The metal complex as claimed in claim 6 , wherein the ligands L are chosen from halogen, CN, CO, alkenes, cycloalkenes and/or alkynes.

8. The metal complex as claimed in claim 6 , wherein ML n represents AuCl, AuCl 3 , PdCl(allyl), RhCl(cod), RhCl(CO) 2 , CuCl, RhCl 4 − and/or BH 3 .

9. A cycloisomerization reaction catalyzed by the metal complex as claimed in claim 6 .

10. The phosphenium compound as claimed in claim 1 , wherein:

R 1 , R 2 , R 3 and R 4 , each independently of one another, are chosen from isopropyl and tert-butyl; and

R 5 and R 6 , each independently of one another, are chosen from linear, branched or cyclic alkyl, alkenyl, or aryl, each of which is unsubstituted or substituted.

11. A phosphenium compound with the general formula I:

in which R 1 , R 2 , R 3 and R 4 are identical or different and are chosen from isopropyl and tert-butyl,

R 5 and R 6 stand for a saturated or unsaturated and linear or branched alkyl group, alkenyl group or aryl group, which can have suitable substituents, or a heteroatom-comprising hydrocarbon group, which can have suitable substituents, and the R 5 and R 6 radicals can form a ring which can be 4- to 20-membered, saturated or unsaturated and alicyclic or heteroalicyclic and can exhibit suitable substituents, and

X − represents an anion.

12. The phosphenium compound as claimed in claim 11 , wherein X − is chosen from BF 4 − , PF 6 − , SbF 6 − and/or BPh 4 − .

Assignments (2)
CHANGE OF NAME Recorded Feb 27, 2023
From: STUDIENGESELLSCHAFT KOHLE MBH
To: STUDIENGESELLSCHAFT KOHLE GGMBH
Reel/Frame 062876/0181 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 23, 2013
From: ALCARAZO, MANUEL; BRUNS, HANS; PETUSKOVA, JEKATERINA
To: STUDIENGESELLSCHAFT KOHLE MBH
Reel/Frame 031256/0572 →
Priority Claims (1)
DE 10 2011 012 334 · Feb 24, 2011 · national
Continuity (1)
Related Publication 20140051870A1 · Feb 20, 2014