IP Library Granted Patent US 8,992,969
Granted Patent B2
US 8,992,969 · App. 14/059,369 · Granted Mar 31, 2015

Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery

Inventor: Praveen Kumar (Kitchener, CA)
Assignee: Helix BioPharma Corporation
A61K47/16A61K38/212A61K9/107
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Quick Facts
Patent No.
US 8,992,969
App. No.
14/059,369
Granted
Mar 31, 2015
Kind
B2
Abstract

This invention relates to biphasic lipid-vesicle compositions and methods for treating cervical displasia by intravaginal delivery.

Claims (5)

1. A method for inhibiting aggregation of interferon alpha-2b in a biphasic vesicle composition which method comprises adding argmine or a pharmaceutically acceptable salt thereof in a sufficient amount to inhibit aggregation of interferon alpha-2b, thereby inhibiting aggregation of interferon alpha-2b in the biphasic vesicle composition.

2. The method of claim 1 , wherein the arginine or a pharmaceutically acceptable salt thereof is arginine hydrochloride.

3. The method of claim 1 , wherein the arginine or a pharmaceutically acceptable salt thereof is L-arginine or a pharmaceutically acceptable salt thereof.

4. The method of claim 1 , wherein the arginine or a pharmaceutically acceptable salt thereof is L-arginine hydrochloride.

5. The method of claim 4 , wherein the L-arginine hydrochloride is present in an amount of 0.1 to 5 mg/g.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2018
From: HELIX BIOPHARMA CORP.
To: XISLE PHARMA VENTURES TRUST
Reel/Frame 044878/0568 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 9, 2018
From: XISLE PHARMA VENTURES TRUST
To: ALTUM-AVRO PHARMA PARTNERSHIP
Reel/Frame 044878/0630 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 6, 2015
From: KUMAR, PRAVEEN
To: HELIX BIOPHARMA CORPORATION
Reel/Frame 034647/0780 →
Continuity (2)
Division 13965122 · Aug 12, 2013
Related Publication 20150044276A1 · Feb 12, 2015