Anti-cancer combination treatment and kit-of-parts

1. A pharmaceutical kit of parts comprising

a) an anti-cancer medicament, and

b) a Basidiomycete bioactive agent, said Basidiomycete being of the genus Lentinus , in solid or liquid form,

wherein said bioactive agent comprises a heteropolymeric polysaccharide comprising the monosaccharide units glucose, galactose and mannose,

wherein said heteropolymeric polysaccharide has a molecular weight in the size range of from 100,000 g/mol to 1,000,000 g/mol,

wherein said bioactive agent is isolated from the liquid growth medium of a liquid culture of the genus Lentinus after the mycelium has been removed from said liquid culture, and

wherein said liquid growth medium is not subjected to alcohol precipitation.

2. The kit according to claim 1 , wherein the bioactive agent is precipitated by ultracentrifugation.

3. The kit according to claim 1 , wherein said anticancer medicament is suitable for administration simultaneously with the administration of the bioactive agent.

4. The kit of claim 1 , further comprising instructions for a dosing regime.

5. The kit of claim 1 , wherein said polysaccharide does not comprise a peptide or a polypeptide.

6. A method of treatment comprising the step of administering the anti-cancer medicament and the bioactive agent of the pharmaceutical kit of parts according to claim 1 to an individual in need thereof according to a set dosage regime.

7. The method of claim 6 , wherein the anti-cancer medicament and the bioactive agent are administered simultaneously.

8. The method of claim 7 , wherein the anti-cancer medicament and the bioactive agent are administered as a co-formulation.

9. The method of claim 6 , wherein the anti-cancer medicament and the bioactive agent are administered sequentially.

10. The kit of claim 1 , wherein the bioactive agent is obtainable from Lentinus edodes.