IP Library Granted Patent US 9,084,760
Granted Patent B2
US 9,084,760 · App. 14/278,771 · Granted Jul 21, 2015

Increasing glutathione levels for therapy

Inventor: Rajagopal V. Sekhar (Missouri City, TX)
Assignee: Baylor College of Medicine
A61K31/198
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Quick Facts
Patent No.
US 9,084,760
App. No.
14/278,771
Granted
Jul 21, 2015
Kind
B2
Abstract

The present invention concerns compositions and methods related to utilizing glycine and N-acetylcysteine for a variety of methods, including, for example, reducing deleterious effects of oxidative stress; treating and/or preventing diabetes; and/or increasing GSH levels.

Claims (8)

1. A method of preventing diabetes in an individual in need thereof, comprising the step of providing an effective amount of glycine and n-acetylcysteine to the individual.

2. The method of claim 1 , wherein the glycine and n-acetylcysteine are provided to the individual in the same composition.

3. The method of claim 1 , wherein the glycine and n-acetylcysteine are provided orally to the individual.

4. A method of treating and/or preventing a medical condition selected from diabetes or complications of diabetes in an individual in need thereof, wherein the medical condition is associated with reduced glutathione levels, comprising the steps of:

a) identifying an individual in need of treatment of the medical condition; and

b) providing an effective amount of glycine and N-acetylcysteine to the individual.

5. A method of increasing GSH levels in an individual in need thereof, comprising the step of providing an effective amount of glycine and n-acetylcysteine to the individual, wherein the individual in need thereof is at least sixty years of age and/or has diabetes.

6. A method of reducing body weight, lowering cholesterol level, and/or lowering triglyceride level in an individual, comprising the step of providing an effective amount of glycine and n-acetylcysteine to the individual.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 23, 2015
From: SEKHAR, RAJAGOPAL V.
To: BAYLOR COLLEGE OF MEDICINE
Reel/Frame 034800/0413 →
Continuity (4)
Continuation 13728903 · Dec 27, 2012
Continuation 12641894 · Dec 18, 2009
Provisional Application 61138591 · Dec 18, 2008
Related Publication 20140288177A1 · Sep 25, 2014