IP Library Granted Patent US 9,102,653
Granted Patent B2
US 9,102,653 · App. 14/322,165 · Granted Aug 11, 2015

Substituted quinazolinones as vanilloid antagonists

Inventors: Timothy John Ritchie (Horsham, GB); Andrew James Culshaw (Horsham, GB); Christopher Thomas Brain (Horsham, GB); Edward Karol Dziadulewicz (Horsham, GB); Terance William Hart (High Peak, GB)
Assignee: NOVARTIS AG
C07D401/04C07D239/91
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Quick Facts
Patent No.
US 9,102,653
App. No.
14/322,165
Granted
Aug 11, 2015
Kind
B2
Abstract

The present specification relates to the use of a quinazolinone compound of the formula (I) wherein R 1 , R 2 , R 3 , R 4 , R 5 and m are as defined in the specification and in the claims, in free form or in salt form, and, where possible, in acid addition salt form.

Claims (3)

1. A method for treating eye pain in a mammal, comprising:

administering to a mammal in need thereof a therapeutically effective amount of a quinazolinone compound of the formula:

in free base form or in pharmaceutically acceptable acid addition salt form.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 6, 2023
From: NOVARTIS AG
To: BAUSCH + LOMB IRELAND LIMITED
Reel/Frame 065790/0208 →
Priority Claims (1)
GB 0412769.2 · Jun 8, 2004 · national
Continuity (4)
Continuation 13434248 · Mar 29, 2012
Continuation 13089943 · Apr 19, 2011
Continuation 11569802
Related Publication 20140315932A1 · Oct 23, 2014