IP Library › Granted Patent US 9,125,655
Granted Patent B2
US 9,125,655 · App. 13/185,377 · Granted Sep 8, 2015

Correction and optimization of wave reflection in blood vessels

Inventors: Morteza Gharib (Altadena, CA); Niema Pahlevan (Pasadena, CA)
Assignee: CALIFORNIA INSTITUTE OF TECHNOLOGY
A61B17/12013A61B5/02A61B2017/00022A61B2019/464A61N1/362
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Quick Facts
Patent No.
US 9,125,655
App. No.
13/185,377
Granted
Sep 8, 2015
Kind
B2
Abstract

The present invention provides methods and modalities that can modify wave reflection in the vascular system in order to create constructive interactions between existing wave dynamics and new reflective waves for the purpose of lowering the workload on the heart and increasing cardiac output, providing a viable option for the prevention and treatment of many heart conditions and diseases.

Claims (7)

1. A system implantable in a mammal along the mammal's aorta, comprising:

a plurality of inelastic members comprising biocompatible material, each member being a fully encircling ring that is set to have the same diameter throughout use in the same location once implanted,

the members positioned around the aorta, each member having a curvature for constricting the aorta and spaced apart from one another to generate a plurality of artificial pressure wave reflection sites in the aorta to reduce a hemodynamic load on the mammal's heart as compared to a hemodynamic load without the artificial pressure wave reflection sites.

2. The device of claim 1 , wherein at least one of the plurality of members consists of a unitary strip of fabric wrapped around the aorta and immobilized by an adhesive or a suture.

3. The device of claim 1 , adapted to be changed by an adjustment, during implantation only.

4. The device of claim 3 , adapted to be changed in at least one parameter for the plurality of members, the parameter selected from an axial distance from the aortic root and a diameter.

5. The device of claim 1 , wherein each of the plurality of members consists of a unitary ring with engaged teeth for diameter adjustment and lock in, and each of the rings consists of plastic.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 20, 2012
From: GHARIB, MORTEZA; PAHLEVAN, NIEMA
To: CALIFORNIA INSTITUTE OF TECHNOLOGY
Reel/Frame 028602/0315 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 9, 2011
From: GHARIB, MORTEZA; PAHLEVAN, NIEMA
To: CALIFORNIA INSTITUTE OF TECHNOLOGY
Reel/Frame 027199/0854 →
Continuity (2)
Provisional Application 61364981 · Jul 16, 2010
Related Publication 20120053672A1 · Mar 1, 2012