IP Library › Granted Patent US 9,138,432
Granted Patent B2
US 9,138,432 · App. 14/150,575 · Granted Sep 22, 2015

Methods for the administration of iloperidone

Inventors: Curt Wolfgang (Germantown, MD); Mihael Polymeropoulos (Potomac, MD)
Assignee: Vanda Pharmaceuticals, Inc.
A61K31/454A61K31/519C12Q1/6883C12Q2600/106C12Q2600/156C12Q2600/172
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Quick Facts
Patent No.
US 9,138,432
App. No.
14/150,575
Granted
Sep 22, 2015
Kind
B2
Abstract

The present invention relates to methods for treating a patient with iloperidone or a metabolite thereof, which patient is also being treated with fluoxetine, and lowering risk for QT prolongation.

Claims (3)

1. A method of decreasing a risk of QT prolongation in a patient being treated for schizophrenia with iloperidone, the method comprising:

administering to the patient a dose of iloperidone that is 24 mg/day if, and because, the patient is not being treated with fluoxetine; and

administering to the patient a dose of iloperidone that is 12 mg/day if, and because, the patient is being treated with fluoxetine.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 21, 2014
From: WOLFGANG, CURT; POLYMEROPOULOS, MIHAEL
To: VANDA PHARMACEUTICALS, INC.
Reel/Frame 032006/0844 →
Continuity (4)
Continuation 14060978 · Oct 23, 2013
Continuation 11576178
Provisional Application 60614798 · Sep 30, 2004
Related Publication 20140128433A1 · May 8, 2014