IP Library Granted Patent US 9,145,359
Granted Patent B2
US 9,145,359 · App. 13/998,958 · Granted Sep 29, 2015

Cyclic process for the production of taurine from monoethanolamine

Inventor: Songzhou Hu (Princeton, NJ)
C07C303/02C07C303/24C07C303/42
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Quick Facts
Patent No.
US 9,145,359
App. No.
13/998,958
Granted
Sep 29, 2015
Kind
B2
Abstract

A method is disclosed for the production of taurine in high yield by a cyclic process of reacting monoethanolamine, sulfuric acid, and ammonium sulfite in the presence of additives to inhibit the hydrolysis of 2-aminoethyl hydrogen sulfate intermediate. The cyclic process is economical and little waste is generated.

Claims (8)

1. A cyclic process for increasing the overall production yield of taurine from monoethanolamine, comprising:

(a) Reacting monoethanol amine with sulfuric acid to form 2-aminoethyl hydrogen sulfate ester;

(b) Carrying out the reaction of 2-aminoethylhydrogen sulfate ester with ammonium sulfite to yield taurine in a buffering system at pH 6.0 to 8.0;

(c) Suppressing the hydrolysis of 2-aminoethyl hydrogen sulfate ester during its reaction with ammonium sulfite by use of hydrolysis inhibitors;

(d) Converting the residual monoethanolamine in the crystallization mother liquor of taurine to 2-aminoethyl hydrogen sulfate ester, which is recycled to step (a) to produce taurine.

2. The process according to claim 1 , wherein the buffering system is composed of ammonium bisulfite and excess ammonium sulfite.

3. The process according to claim 1 , wherein hydrolysis inhibitors are monoethanolamine, diethanolamine, triethanolamine, and dimethylaminoethanol.

4. The process according to claim 1 , wherein the residual monoethanolamine in the crystallization mother liquor of taurine is reacted with sulfuric acid in the presence of ammonium sulfate to regenerate 2-aminoethyl hydrogen sulfate ester intermediate.

Assignments (3)
CORRECTIVE ASSIGNMENT TO CORRECT THE CORRESPONDENCE DATA PREVIOUSLY RECORDED ON REEL 72544 FRAME 405. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 15, 2025
From: VITAWORKS IP, LLC
To: LIBRE HOLDINGS INC.
Reel/Frame 073067/0435 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2025
From: VITAWORKS IP, LLC
To: LIBRE HOLDINGS INC.
Reel/Frame 072544/0405 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 30, 2019
From: HU, SONGZHOU
To: VITAWORKS IP, LLC
Reel/Frame 049319/0601 →
Continuity (1)
Related Publication 20150183731A1 · Jul 2, 2015