Methods of use for a natural Thomsen-Friedenreich disaccharide compound
A Thomsen-Friedenreich disaccharide-containing glycopeptide purified from cod fish of approximately 100 kDa (designated TFD 100 ) and methods of using the same in the suppression of cancer metastasis is disclosed.
1. A method of suppressing metastasis in a subject comprising administering an effective amount of a TFD-containing glycopeptide to a subject having cancer, wherein the TFD-containing glycopeptide is TFD 100 , thereby suppressing metastasis in a subject.
2. The method of claim 1 , wherein the cancer is prostate cancer.
3. The method of claim 1 , wherein a pharmaceutical formulation comprising from about 5 mg/kg to about 50 mg/kg of the TFD-containing glycopeptide to body weight is administered to the subject.
4. The method of claim 1 , wherein the subject is a human.