Integrated system for sampling and analysis

1. A device for determination of a sample from a dielectric fluid medium for a bio-specific assay device, comprising: a sampling device and a biosensor, wherein the sampling device comprises an ionic propulsion device that concentrates a sample from dielectric fluid medium by electrically focusing the sample on to a delimited area of a capture element and wherein said biosensor is fluidically linked to said capture element thus providing sampling and determination in a unitary device.

2. A device according to claim 1 wherein the delimited area results in sample concentration and interrogation of a small volume thus resulting in improved sensitivity.

3. A device according to claim 1 wherein said biosensor comprises an optical sensor device.

4. A device according to claim 3 wherein said optical sensor device is a white light interference spectroscopy device.

5. A device according to claim 3 wherein said optical sensor device is a fluorescent microparticle-based sensing system.

6. A device according to claim 3 wherein the optical sensor device measures shifts in wavelength light.

7. A device according to claim 6 wherein the optical sensor device measures optical interference.

8. A device according to claim 6 wherein the optical sensor device measures color of fluorescent microparticles.

9. A device according to claim 8 wherein the wavelength shift is determined from color values of pixels.

10. A device according to claim 6 wherein the wavelength shift is determined by means of a spectrophotometer.

11. A device according to claim 6 wherein the wavelength shift is measured by a digital imaging device.

12. A device according to claim 1 wherein said biosensor comprises an electrical sensing device.

13. A device according to claim 12 wherein said electrical sensing device comprises a field-effect transistor device.

14. A device according to claim 12 where said electrical sensing device comprises a magneto-resistive device.