IP Library Granted Patent US 9,221,874
Granted Patent B2
US 9,221,874 · App. 13/357,189 · Granted Dec 29, 2015

Antiviral peptides against influenza virus

Inventors: Stacey L. Schultz-Cherry (Germantown, TN); Curtis R. Brandt (Stoughton, WI); Jeremy C. Jones (Memphis, TN)
Assignee: Wisconsin Alumni Research Foundation
C07K7/08C07K7/06C07K14/50A61K38/00
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Quick Facts
Patent No.
US 9,221,874
App. No.
13/357,189
Granted
Dec 29, 2015
Kind
B2
Abstract

The present disclosure generally relates to peptides having antiviral properties. More particularly, the invention relates to peptides exhibiting activity against influenza viruses, to pharmaceutical compositions comprising the peptides, and to methods of using the peptides to prevent and/or treat influenza viral infections.

Claims (9)

1. An antiviral peptide, wherein the antiviral peptide is SEQ ID NO: 44.

2. A composition comprising the peptide of SEQ ID NO: 44 and a pharmaceutically acceptable carrier.

3. A method of treating or inhibiting an influenza A viral respiratory infection in a mammal, the method comprising administering to the mammal an effective amount of an antiviral peptide, wherein the antiviral peptide is SEQ ID NO: 44.

4. The method of claim 3 wherein the antiviral peptide is administered with a pharmaceutically acceptable carrier.

5. The method of claim 3 wherein the antiviral peptide is administered through parenteral administration.

6. The method of claim 3 wherein the antiviral peptide is administered intranasally.

7. The method of claim 3 wherein the antiviral peptide is administered prophylactally.

8. The method of claim 3 wherein the antiviral peptide is administered after the mammal has been exposed to influenza A.

9. The method of claim 3 wherein the antiviral peptide is administered to the mammal at about the time the mammal is exposed to influenza A.

Assignments (2)
CONFIRMATORY LICENSE Recorded May 17, 2018
From: WISCONSIN ALUMNI RESEARCH FOUNDATION
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 046834/0145 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 28, 2015
From: JONES, JEREMY; SCHULTZ-CHERRY, STACEY; BRANDT, CURTIS
To: WISCONSIN ALUMNI RESEARCH FOUNDATION
Reel/Frame 036665/0468 →
Continuity (3)
Division 12484853 · Jun 15, 2009
Provisional Application 61061503 · Jun 13, 2008
Related Publication 20130190228A1 · Jul 25, 2013