IP Library Granted Patent US 9,234,952
Granted Patent B2
US 9,234,952 · App. 13/792,663 · Granted Jan 12, 2016

System and method for determining k-space views and diffusion weighting directions using centroidal voronoi tessellations

Inventor: Cheng Guan Koay (Madison, WI)
Assignee: WISCONSIN ALUMNI RESEARCH FOUNDATION
G01R33/4826G01R33/56341
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,234,952
App. No.
13/792,663
Granted
Jan 12, 2016
Kind
B2
Abstract

Described here are a system and method for generating uniform antipodally symmetric point sets that define diffusion-weighting directions or three-dimensional radial k-space trajectories for magnetic resonance imaging. The point sets are generated robustly and efficiently using a constrained centroidal Voronoi tessellation endowed with a pseudometric. This pseudometric is derived from a measure of the electrostatic energy of points distributed on a hemispherical surface.

Claims (63)

1. A method for producing an image of a subject with a magnetic resonance imaging (MRI) system, the steps of the method comprising:

a) determining MRI acquisition parameters by generating a point set that defines the MRI acquisition parameters, each point being computed as a generator of a centroidal Voronoi tessellation that is formed using a pseudometric on a sphere that enforces antipodal symmetry of points distributed on a hemisphere of the sphere, the point set defining points that are substantially uniformly and antipodally distributed on a surface of the sphere;

b) directing the MRI system to acquire k-space data from a subject using the MRI acquisition parameters determined in step a); and

c) reconstructing an image of the subject from the k-space data acquired in step b).

2. The method as recited in claim 1 in which the MRI acquisition parameters determined in step a) include at least one of a k-space trajectory and a diffusion-weighting gradient direction.

3. The method as recited in claim 2 in which the k-space trajectory is a three-dimensional radial k-space trajectory.

4. The method as recited in claim 1 in which step a) includes providing a set of initial generators; determining a centroidal Voronoi tessellation for each initial generator; and iteratively updating the centroidal Voronoi tessellations using the pseudometric.

5. The method as recited in claim 4 in which determining the centroidal Voronoi tessellation for each initial generator includes:

selecting one of the initial generators;

identifying surrounding generators within a specified distance of the selected initial generator; and

computing vertices of the centroidal Voronoi tessellation by computing a convex hull using the selected initial generator and the identified surrounding generators.

6. The method as recited in claim 5 in which the vertices of the centroidal Voronoi tessellation are computed by:

rotating the selected initial generator and the identified surrounding generators such that the selected initial generator lies on a z-axis; and

stereographically projecting the identified surrounding generators onto an x-y plane.

7. The method as recited in claim 5 in which the specified distance is based on a radius of a spherical cap centered on the selected initial generator.

8. The method as recited in claim 1 in which the pseudometric is based on a measure of electrostatic energy of points distributed on the hemisphere of the sphere.

9. The method as recited in claim 8 in which the pseudometric has the following form:

(

1

r

ij

+

1

4

-

r

ij

2

)

-

1

;

wherein r ij is a Euclidean distance between two points on the surface of the hemisphere.

10. The method as recited in claim 1 in which the pseudometric has the following form:

(

1

r

ij

n

+

1

(

4

-

r

ij

2

)

n

/

2

)

-

1

;

wherein r ij is a Euclidean distance between two points on the surface of the hemisphere and n is a positive integer.

11. A method for producing an image of a subject with a magnetic resonance imaging (MRI) system, the steps of the method comprising:

a) providing a look-up table that defines points on a sphere that are substantially uniformly distributed on the surface of the sphere, each point corresponding to a centroid of a centroidal Voronoi tessellation that is defined by a pseudometric that enforces antipodal symmetry on the sphere;

b) determining MRI acquisition parameters using the provided look-up table;

c) directing the MRI system to acquire k-space data from a subject using the MRI acquisition parameters determined in step b); and

d) reconstructing an image of the subject from the k-space data acquired in step c).

12. The method as recited in claim 11 in which the MRI acquisition parameters determined in step b) include at least one of a k-space trajectory and a diffusion-weighting gradient direction.

13. The method as recited in claim 12 in which the k-space trajectory is a three-dimensional radial k-space trajectory.

Assignments (2)
CONFIRMATORY LICENSE Recorded May 17, 2018
From: WISCONSIN ALUMNI RESEARCH FOUNDATION
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 046179/0483 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 2, 2015
From: KOAY, CHENG
To: WISCONSIN ALUMNI RESEARCH FOUNDATION
Reel/Frame 036937/0043 →
Continuity (1)
Related Publication 20140253118A1 · Sep 11, 2014