Solid film, rapidly dissolvable in liquids
A solid film rapidly dissolvable in liquids, in particular biological liquids, to release pharmaceutical, cosmetic and nutrient substances. The solid film is also soluble in biological organic liquids to protect wounds of the human body by releasing cicatrizing, disinfectant and cosmetic substances. The film can also be used to release flavoring substances directly onto moist nutrient products.
1. A solid film rapidly dissolvable in liquids and configured to have cicatizing filmogenic action for treating a small wound and/or an aphtha, comprising 25% and 60% of sodium alginate, 0.1% and 20% of microcrystalline cellulose, 0.1% and 25% of a vegetable protein, 5 to 12% polysorbate 60 or polysorbate 80, 15 to 45% of glycerin, sorbitol, or a combination thereof, the percentages being by weight on the weight of the finished solid film, and water, wherein the vegetable protein yields a water activity (A w ) of the solid film of between 0.1 and 0.3 and is the only preservation of the solid film and wherein the solid film is made by a process that comprises forming a film in a ventilated tunnel oven comprising four successive heating stations with a first heating station having a temperature of 60 to 80° C., a second heating station having a temperature of 70 to 90° C., a third heating station having a temperature of 70 to 90° C., and a fourth heating station having a temperature of 60 to 80° C.
2. The film as claimed in claim 1 , having a dissolution time between 10 and 20 seconds.
3. The film as claimed in claim 1 , further comprising at least one substance selected from the group consisting of an emulsifying product, an emulsifier/texturizer, a plasticizing/wetting agent, a filmogen, an aromatizer, a product with pharmacological activity, a product with cosmetic activity and a product with an alimentary property.
4. The film as claimed in claim 3 , comprising an emulsifying or emulsifying/texturizing product selected from the group consisting of a polyoxyethylene derivative, a natural gum, a natural emulsifier, a cellulose derivative, and a starch.
5. The film as claimed in claim 3 , comprising a plasticizing/wetting product selected from the group consisting of a polyol and an ester of acetic acid with glycerol.
6. The film as claimed in claim 3 , comprising a filmogenic substance selected from the group consisting of a glycosamine glycan, a mucopolysaccharide, and a water-soluble polysaccharide.
7. The film as claimed in claim 1 , comprising 5 to 12% of polysorbate 80.
8. The film as claimed in claim 3 , comprising carob seed flour or acacia gum.
9. The film as claimed in claim 3 , comprising gelatin.
10. The film as claimed in claim 3 , comprising carboxymethyl cellulose or methylcellulose.
11. The film as claimed in claim 3 , comprising maize starch or potato starch.
12. The film as claimed in claim 5 , comprising glycerin, sorbitol or propylene glycol.
13. The film as claimed in claim 6 , comprising hyaluronic acid.
14. The film as claimed in claim 6 , comprising pullulan.
15. The film as claimed in claim 1 , further comprising loperamide hydrochloride or melatonin.
16. The film as claimed in claim 15 , comprising 15 to 45% of a combination of glycerin and sorbitol.
17. The film as claimed in claim 1 , comprising 15 to 45% of a combination of glycerin and sorbitol.
18. The film as claimed in claim 1 , having a thickness between 60 and 150 μm.
19. A method of treating a small wound and/or an aphtha in a subject, the method comprising providing the film as claimed in claim 1 to provide cicatizing filmogenic action for treating the small wound and/or the aphtha.
20. A method of treating a small wound and/or an aphtha in a subject, the method comprising providing the film as claimed in claim 15 to provide cicatizing filmogenic action for treating the small wound and/or the aphtha.
21. A method of treating a small wound and/or an aphtha in a subject, the method comprising providing the film as claimed in claim 16 to provide cicatizing filmogenic action for treating the small wound and/or the aphtha.
22. A method of treating a small wound and/or an aphtha in a subject, the method comprising providing the film as claimed in claim 17 to provide cicatizing filmogenic action for treating the small wound and/or the aphtha.