IP Library Granted Patent US 9,296,782
Granted Patent B2
US 9,296,782 · App. 13/934,090 · Granted Mar 29, 2016

Inhibitors of hepatitis C virus

Inventors: Kyla Bjornson (San Lorenzo, CA); Eda Canales (San Mateo, CA); Jeromy J. Cottell (Redwood City, CA); Kapil Kumar Karki (Foster City, CA); Ashley Anne Katana (San Mateo, CA); Darryl Kato (San Francisco, CA); Tetsuya Kobayashi (Sunnyvale, CA); John O. Link (San Francisco, CA); Ruben Martinez (South San Francisco, CA); Barton W. Phillips (San Mateo, CA); Hyung-Jung Pyun (Fremont, CA); Michael Sangi (Oakland, CA); Adam James Schrier (Redwood City, CA); Dustin Siegel (Foster City, CA); James G. Taylor (San Mateo, CA); Chinh Viet Tran (San Diego, CA); Teresa Alejandra Trejo Martin (Union City, CA); Randall W. Vivian (San Mateo, CA); Zheng-Yu Yang (Palo Alto, CA); Jeff Zablocki (Los Altos, CA); Sheila Zipfel (San Mateo, CA)
Assignee: Gilead Sciences, Inc.
C07K5/08A61K31/4745A61K31/4985A61K31/506A61K31/519A61K38/06A61K38/21A61K45/06C07D498/16C07D498/22C07K5/0808C07K5/0812C07K5/0827A61K38/00
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Quick Facts
Patent No.
US 9,296,782
App. No.
13/934,090
Granted
Mar 29, 2016
Kind
B2
Abstract

Compounds of Formula I are disclosed As well as pharmaceutically acceptable salts thereof. Methods of using said compounds and pharmaceutical compositions containing said compounds are also disclosed.

Claims (24)

1. A compound of Formula lVa:

or a pharmaceutically acceptable salt thereof.

2. A compound of claim 1 which is:

or a pharmaceutically acceptable salt thereof.

3. A compound of Formula lVc:

or a pharmaceutically acceptable salt thereof.

4. A compound of claim 3 which is:

or a pharmaceutically acceptable salt thereof.

5. A compound of Formula lVe:

or a pharmaceutically acceptable salt thereof.

6. A compound of claim 5 which is:

or a pharmaceutically acceptable salt thereof.

7. A compound of formula lVg:

or a pharmaceutically acceptable salt thereof.

8. A compound of claim 7 which is:

or a pharmaceutically acceptable salt thereof.

9. A compound which is:

10. A composition comprising the compound of claim 9 and a pharmaceutically acceptable carrier.

11. A compound which is:

12. A composition comprising the compound of claim 11 and a pharmaceutically acceptable carrier.

13. A compound which is:

14. A composition comprising the compound of claim 13 and a pharmaceutically acceptable carrier.

15. A compound which is:

16. A composition comprising the compound of claim 15 and a pharmaceutically acceptable carrier.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 22, 2019
From: GILEAD SCIENCES, INC.
To: GILEAD PHARMASSET LLC
Reel/Frame 048958/0911 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 1, 2013
From: BJORNSON, KYLA; CANALES, EDA; COTTELL, JEROMY J.; KARKI, KAPIL K.; KATANA, ASHLEY A.; KATO, DARRYL; KOBAYASHI, TETSUYA; LINK, JOHN O.; ZIPFEL, SHEILA; MARTINEZ, RUBEN; SCHRIER, ADAM J.; SIEGEL, DUSTIN; TAYLOR, JAMES G.; TRAN, CHINH V.; TREJO-MARTIN, TERESA A.; VIVIAN, RANDALL W.; YANG, ZHENG-YU; ZABLOCKI, JEFF; PHILLIPS, BARTON W.; PYUN, HYUNG-JUNG; SANGI, MICHAEL
To: GILEAD SCIENCES, INC.
Reel/Frame 031322/0968 →
Continuity (3)
Provisional Application 61667806 · Jul 3, 2012
Provisional Application 61798524 · Mar 15, 2013
Related Publication 20140017198A1 · Jan 16, 2014