IP Library › Granted Patent US 9,370,460
Granted Patent B2
US 9,370,460 · App. 14/427,888 · Granted Jun 21, 2016

Systems and methods for treating amblyopia by visual stimulation of the brain

Inventors: Ilan Vadai (Hod-Hasharon, IL); Yuval Avni (Tel-Aviv, IL)
Assignee: Visior Technologies, LTD
A61H5/00A61B3/032A61B3/08A61B3/085G02B27/017A61H2201/1604A61H2201/165A61H2201/5007A61H2201/5015A61H2201/5097
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Quick Facts
Patent No.
US 9,370,460
App. No.
14/427,888
Granted
Jun 21, 2016
Kind
B2
Abstract

A system for treating amblyopia through the visual stimulation of the brain through a predetermined regime is provided. The system for treating amblyopia comprises a headmountable visual content display device, a controller unit, a visual content source, a data storage device, a graphic processing unit and an audio source. A protocol useful for treating amblyopia by visual stimulation of the brain is also provided. A predetermined regime useful for treating amblyopia by stimulation of the brain is additionally provided.

Claims (61)

1. A system useful for treating amblyopia by stimulation configured to increase brain blood flow of a user, comprising:

a head mountable visual display device having at least one displaying area and coupled to a controller unit, the controller unit configured to alter presentation of a video image in a streaming video content in real time for presenting the video image to each eye of the user in accordance with a pre-determined stimulation regime;

an audio device configured to provide an audio stimulation to each ear of the user according to the pre-determined stimulation regime;

the pre-determined stimulation regime further including at least one visibly noticed intensity alteration of an image parameter defining the video image presented on at least one display area of the head mountable visual display device;

the controller unit further configured to provide the pre-determined stimulation regime;

wherein, the pre-determined stimulation regime applies a modifying step by altering the image parameter at a frequency configured to be in a range of 0.5-60 Hz; and

wherein the image parameter is selected from the group consisting of contrast, brightness, sharpness, saturation, resolution, and any combination thereof; and

wherein the audio device further provides the audio stimulation according to the pre-determined stimulation regime by differing ear volume administered proximal to a side of the user having a deficient eye from that administered proximal to another side of the user not having the deficient eye.

2. The system of claim 1 , wherein the intensity alteration of the image parameter is configured to be in a range of −99% to +99% of the image parameter defining the presented video image.

3. The system of claim 1 , wherein the audio device is configured to provide audio stimulation according to said predetermined stimulation regime by elevating ear volume administered proximal to the side of the user having the deficient eye, and by reducing ear volume administered proximal to another side of the user not having the deficient eye.

4. The system of claim 1 , wherein said controller unit additionally comprises a data storage device adapted to be operatively connected to said controller unit configured to store said predetermined stimulation regime.

5. The system of claim 1 , wherein said controller unit comprises a graphic processing unit configured to alter said at least one display parameter according to said predetermined stimulation regime.

6. The system of claim 1 , wherein said at least one display parameter is displayed enhanced to the deficient eye and displayed dampened to the fellow eye.

7. The system of claim 1 , wherein said controller unit is additionally configured to insert, based on the pre-determine stimulation regime, at least one overlay object of at least one object on said at least one displaying area.

8. The system of claim 7 , wherein said controller unit is additionally configured to trigger audio stimuli associated with at least one overlay object according to said predetermined stimulation regime.

9. The system of claim 7 , wherein said controller unit is additionally configured to synchronize audio to the insertion of at least one overlay of at least one object according to said predetermined stimulation regime.

10. The system of claim 1 , wherein said controller unit is additionally configured to introduce based on the pre-determined stimulation regime at least one flicker event on said at least one displaying area.

11. The system of claim 10 , wherein said controller unit is additionally configured to insert the at least one flicker event displayed to the deficient eye, wherein the flicker event occurs by displaying a sequence of frames that are not part of original frames in the video.

12. A process useful for treating amblyopia by stimulation configured to increase brain blood flow of a user comprising:

placing a head mountable visual display device on a user, the device having at least one displaying area and coupled to a controller unit, the controller unit configured to alter presentation of a video image in a streaming video content in real time for presenting the video image to each eye of the user in accordance with a pre-determined stimulation regime;

having an audio device operatively connected to the head mountable visual display, the audio device configured to provide an audio stimulation to each ear of the user according to the pre-determined stimulation regime;

having the pre-determined stimulation regime further including at least one visibly noticed intensity alteration of an image parameter defining the video image presented on at least one display area of the head mountable visual display device;

having the controller unit further configured to provide the pre-determined stimulation regime;

wherein, the pre-determined stimulation regime applies a modifying step by altering the image parameter at a frequency configured to be in a range of 0.5-60 Hz; and

wherein the image parameter is selected from the group consisting of contrast, brightness, sharpness, saturation, resolution, and any combination thereof; and

wherein the pre-determined stimulation regime is affecting properties of the audio stimulation in conjunction to the modifying step of the image parameter; and

wherein the audio device further provides the audio stimulation according to the pre-determined stimulation regime by differing ear volume administered proximal to a side of the user having a deficient eye from that administered proximal to another side of the user not having the deficient eye.

13. The process of claim 12 , wherein said visual display device is configured to display in a dichoptic presentation selected from the group consisting of Side by Side, Frame Sequential, and Field Sequential presentation.

14. A predetermined regime useful for increasing the cerebral blood flow in the visual system of an amblyopic patient comprising

modifying at least one displaying area by changing a display parameter affecting display presentation at the frequency configured to be in the range of 0.5-60 Hz;

altering at least one visibly noticed intensity of the display parameter defining a video image presented on at least one display area of a head mountable visual display device;

selecting the display parameter from the group consisting of contrast, brightness, sharpness, saturation, resolution, and any combination thereof; and

wherein the pre-determined visual stimulation regimen is affecting properties of audio stimulation in conjunction to the modifying step of the display parameter; and

wherein an audio device further providing the audio stimulation according to the pre-determined stimulation regime by differing ear volume administered proximal to a side of the user having a deficient eye from that administered proximal to another side of the user not having the deficient eye; and

wherein said modification is configured to increase the cerebral blood flow in the visual system in comparison to a regime lacking said modifications.

15. The regime of claim 14 , wherein said predetermined stimulation regime additionally comprises introducing at least one flicker event.

16. The regime of claim 14 , wherein said predetermined stimulation regime additionally comprises triggering an audio stimulation configured to be administered to at least one ear by elevating ear volume administered proximal to the side of the user having the deficient eye, and by reducing ear volume administered proximal to another side of the user not having the deficient eye.

17. The regime of claim 14 , wherein said predetermined stimulation regime is additionally configured to insert at least one overlay of at least one object on a video content displayed on said at least one displaying area.

18. The regime of claim 14 , wherein said modifying step is configured to alter the level of said at least one display parameter within a range of 99% to +99% of an intensity of said at least one display parameter of a streamed video content.

19. The regime of claim 14 ,

wherein said predetermined stimulation regime additionally comprises triggering an audio stimulation configured to be administered to at least one ear; and

wherein said predetermined stimulation regime is additionally configured to insert at least one overlay of at least one object on said video content displayed on said at least one displayed area; and

wherein said step of inserting said at least one overlay of said at least one object is configured to be coherently connected to said triggering of said audio stimulation.

20. The regime of claim 14 , wherein said predetermined stimulation regime is configured to operate in real time.

21. A visual stimulation regime for a binocular image display device comprising

providing at least one visibly noticeable intensity alteration of at least one display parameter to at least one display area; said intensity alteration of said display parameter is applied to said at least one display area in a range of −99% to +99% of said intensity of said display parameter;

providing an audio device configured to provide an audio stimulation to each ear of a user according to the pre-determined stimulation regime;

the pre-determined stimulation regime further including at least one visibly noticed intensity alteration an image parameter defining the video image presented on at least one display area of the head mountable visual display device;

the controller unit further configured to provide the pre-determined stimulation regime;

wherein, the pre-determined stimulation regime applies a modifying step by altering the image parameter at a frequency configured to be in a range of 0.5-60 Hz; and

wherein the image parameter is selected from the group consisting of contrast, brightness, sharpness, saturation, resolution, and any combination thereof; and

wherein the audio device further provides the audio stimulation according to the pre-determined stimulation regime by differing ear volume administered proximal to a side of the user having a deficient eye from that administered proximal to another side of the user not having the deficient eye.

22. The regime of claim 21 , wherein said predetermined stimulation regime additionally comprises at least one visibly noticeable intensity alteration of at least one value of at least one image parameter defining a video image as presented on the at least one display area; said intensity alteration of said image parameter values is configured to be in the range of −99% to +99% of said intensity of said image parameter defining the presented video image.

23. A visual stimulation regime for an image display device comprises

providing at least one visibly noticeable intensity alteration of at an image parameter defining a video image as presented on at least one display area; said intensity alteration of said image parameter is configured to be in a range of −99% to +99% of said intensity of said image parameter, wherein said image parameter is selected from the group consisting of contrast, brightness, sharpness, saturation, resolution or other conventional parameters and any combination thereof;

providing an audio device configured to provide an audio stimulation to each ear of a user according to the pre-determined stimulation regime;

the pre-determined stimulation regime further including at least one visibly noticed intensity alteration said image parameter defining the video image presented on at least one display area of the head mountable visual display device;

the controller unit further configured to provide the pre-determined stimulation regime;

wherein, the pre-determined stimulation regime applies a modifying step by altering said image parameter at a frequency configured to be in a range of 0.5-60 Hz; and

wherein said image parameter is selected from the group consisting of contrast, brightness, sharpness, saturation, resolution, and any combination thereof; and

wherein the audio device further provides the audio stimulation according to the pre-determined stimulation regime by differing ear volume administered proximal to a side of the user having a deficient eye from that administered proximal to another side of the user not having the deficient eye.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 16, 2015
From: VADAI, ILAN; AVNI, YUVAL
To: VISIOR TECHNOLOGIES, LTD
Reel/Frame 036107/0498 →
Continuity (3)
Provisional Application 61827594 · May 26, 2013
Provisional Application 61700903 · Sep 14, 2012
Related Publication 20150305964A1 · Oct 29, 2015