IP Library Granted Patent US 9,375,407
Granted Patent B2
US 9,375,407 · App. 14/685,008 · Granted Jun 28, 2016

Dimethyl trisulfide as a cyanide antidote

Inventors: Gary A. Rockwood (Baltimore, MD); Ilona Petrikovics (Huntsville, TX); Steven I. Baskin (Huntsville, TX)
Assignees: Sam Houston State University; U.S. Army, Secretary of the Army
A61K31/105
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Quick Facts
Patent No.
US 9,375,407
App. No.
14/685,008
Granted
Jun 28, 2016
Kind
B2
Abstract

Dimethyl trisulfide (DMTS) antidote compositions may be used to as a cyanide poisoning antidote.

Claims (10)

1. A method of treating cyanide intoxication in a subject, comprising:

administrating to a subject who would benefit from such treatment a therapeutically effective amount of dimethyl trisulfide (DMTS).

2. The method of claim 1 , wherein the DMTS is administered transdermally.

3. The method of claim 1 , wherein the DMTS is administered via an aerosol delivery system.

4. The method of claim 1 , wherein the DMTS is administered intramuscularly.

5. The method of claim 1 , wherein the DMTS is administered subcutaneously.

6. The method of claim 1 , wherein the DMTS is administered intra-osseously.

7. The method of claim 1 , wherein the DMTS is administered sublingually.

8. The method of claim 1 , wherein the DMTS is administered as an eye drop in a solution.

9. The method of claim 1 , wherein the DMTS is administered as a rectal administration via a rectal delivery system.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 11, 2023
From: ROCKWOOD, GARY A.
To: THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY
Reel/Frame 063284/0092 →
CONFIRMATORY LICENSE Recorded Jun 21, 2017
From: SAM HOUSTON STATE UNIVERSITY
To: US ARMY, SECRETARY OF THE ARMY
Reel/Frame 042936/0407 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 30, 2016
From: PETRIKOVICS, ILONA
To: SAM HOUSTON STATE UNIVERSITY
Reel/Frame 038134/0939 →
Continuity (2)
Provisional Application 61978501 · Apr 11, 2014
Related Publication 20150290143A1 · Oct 15, 2015