Metal implants
A metal implant for use in a surgical procedure is provided with a surface layer that is integral with the metal substrate, and which incorporates a biocidal material. The surface layer may be grown from the metal substrate, by anodizing, and the biocidal material incorporated in it by ion exchange. Alternatively the layer may be deposited by electroplating, followed by diffusion bonding so as to become integral with the metal substrate. In either case, silver is a suitable biocidal material; and both the release rate and the quantity of biocidal material should be low to avoid toxic effects on body cells. Electropolishing the surface before formation of the surface layer is also beneficial, and this may be achieved by electropolishing.
1. An implant for use in a surgical procedure, the implant comprising:
a metal substrate; and
(ii) an anodized surface layer that is integral with the metal substrate and that consists of:
(a) material selected from a metal oxide, a metal phosphate and a combination thereof; and
(b) a biocidal metal in ionic form; and
wherein the biocidal metal in ionic form is releasable over time from the surface layer, wherein the quantity and release of the biocidal metal are such as to kill bacteria in a vicinity of the implant, to minimize toxic effects on body cells, and to be effective in suppressing infection after the surgical procedure.
2. An implant as claimed in claim 1 wherein the surface layer comprises metal phosphate.
3. An implant as claimed in claim 1 wherein the biocidal metal comprises silver.
4. An implant as claimed in claim 1 wherein the biocidal metal is effective in suppressing infection for at least 6 weeks after the surgical procedure.
5. An implant as claimed in claim 1 wherein the metal substrate comprises a titanium alloy consisting essentially of titanium, aluminium and vanadium.