Vial spiking assemblies and related methods
This disclosure relates to vial spiking assemblies and related methods. In certain aspects, the vial spiking assemblies include a vial adapter having a base, a spike extending from a central region of the base, and a sidewall extending from the base and surrounding the spike. The base and the sidewalls partially, define a cavity that is configured to receive at least a portion of the vial. The assemblies also include a spike cover that is removably attached to the spike and that includes a material configured to indicate when the material is contacted with liquid.
1. A vial spiking assembly comprising:
a vial adapter comprising:
a base;
a spike extending from a central region of the base; and
a sidewall extending from the base and substantially surrounding the spike, the base and the side wall at least partially defining a cavity configured to receive a portion of a vial; and
a spike cover removably attachable to the spike, wherein the spike cover comprises a microporous material configured to indicate when the material has been contacted with liquid, wherein the microporous material has an average pore size capable of permitting air to flow therethrough and preventing liquid from flowing therethrough.
2. The assembly of claim 1 , wherein the microporous material is a color changing material that changes color when contacted by a liquid.
3. The assembly of claim 2 , wherein the color changing material is a microporous material impregnated with at least one of the following: bromophenol blue, cobalt chloride, a food dye, powder dye, and a color additive.
4. The assembly of claim 1 , wherein the microporous material is molded with a color additive that changes color when contacted with liquid.
5. The assembly of claim 1 , wherein the microporous material surrounds the spike when the spike cover is attached to the spike.
6. The assembly of claim 1 , wherein the spike cover is movable away from the base from a first position wherein the cover at least partially covers a tip of the spike of the vial adapter to a second position wherein the tip of the vial adapter is fully exposed.
7. The assembly of claim 1 , wherein the spike cover comprises a housing defining a cavity in which the microporous material is disposed.
8. The assembly of claim 7 , wherein the housing is formed of a gas permeable material.
9. The assembly of claim 7 , wherein the microporous material is visible through the housing.
10. A dialysis system comprising:
a dialysis machine comprising:
a blood pump; and
a drug pump;
a blood line set comprising a blood line that can be operably connected to the blood pump and a drip chamber in fluid communication with the blood line; and
a fluid line set comprising a fluid line that can be connected to the drip chamber of the blood line set and to a vial adapter, the vial adapter comprising:
a base;
a spike extending from a central region of the base; and
a sidewall extending from the base and substantially surrounding the spike, the base and the side wall at least partially defining a cavity configured to receive a portion of a vial; and
a spike cover removably attachable to the spike, wherein the spike cover comprises a microporous material configured to indicate when the material has been contacted with liquid, wherein the microporous material has an average pore size capable of permitting air to flow through and preventing liquid from flowing through.
11. The dialysis system of claim 10 , wherein the microporous material is a color changing material that changes color when contacted by a liquid.
12. The dialysis system of claim 10 , wherein the drip chamber is downstream of the blood pump and the fluid line is connected to a top region of the drip chamber.
13. The dialysis system of claim 11 , wherein the color changing material is a microporous material impregnated with at least one of the following: bromophenol blue, cobalt chloride, a food dye, powder dye, and a color additive.
14. The dialysis system of claim 11 , wherein the microporous material is covalently bonded with a color additive that changes color when contacted with liquid.
15. The dialysis system of claim 10 , wherein the microporous material surrounds the spike when the spike cover is attached to the spike.
16. The dialysis system of claim 10 , wherein the spike cover comprises a housing defining a cavity in which the microporous material is disposed.
17. The dialysis system of claim 16 , wherein the housing is formed of a gas permeable material.
18. The dialysis system of claim 16 , wherein the microporous material is visible through the housing.
19. The dialysis system of claim 10 , wherein the drip chamber is downstream of the blood plump.
20. The dialysis system of claim 10 , wherein the fluid line is connected to a top portion of the drip chamber.
21. The dialysis system of claim 10 , wherein the dialysis machine is configured to pump priming fluid through the fluid line set toward the vial adapter until the priming fluid contacts the microporous material.
22. The dialysis system of claim 10 , wherein the dialysis machine is configured to pump priming fluid through the blood line set in a manner to overfill the drip chamber and cause the priming fluid to flow through the fluid line set toward the vial adapter, until the priming fluid contacts the microporous material.
23. The vial spiking assembly of claim 1 , wherein the microporous material forms an exterior of the spike cover.
24. The dialysis system of claim 10 , wherein the microporous material forms an exterior of the spike cover.