Chroman-derived anti-androgens for treatment of androgen mediated disorders
Methods for the prevention and/or alleviation of androgen-mediated disorders treatable by administering a chroman-derived anti-androgen compound are provided by the present invention. The invention further provides pharmaceutical and nutraceutical compositions containing chroman-derived anti-androgen compounds useful in the prevention and/or alleviation of androgen-mediated disorders, particularly prostate cancer.
1. A method of providing nutraceutical benefits to a human patient comprising the step of administering to the patient a nutraceutical composition including:
(a) a compound having the formula:
(b) a pharmaceutically-acceptable salt of said compound; and
(c) an acceptable carrier,
wherein the nutraceutical benefits comprise treating an androgen-related disorder selected from the group consisting of hirsutism, acne, seborrhea, androgenic alopecia, hyperpilosity, benign prostatic hypertrophy, adenomas or neoplasias of the prostate, benign or malignant tumor cells containing the androgen receptor, osteoporosis, cachexia, endometriosis, polycystic ovary syndrome, male sexual dysfunction, female sexual dysfunction and infertility.
2. The method of claim 1 wherein said nutraceutical composition further comprises an immune boosting agent, anti-inflammatory agent, anti-oxidant agent, or a mixture thereof.