IP Library Granted Patent US 9,458,464
Granted Patent B2
US 9,458,464 · App. 14/312,152 · Granted Oct 4, 2016

Treatment of neuropathic pain

Inventor: Yuanxiang Tao (Boonton, NJ)
Assignee: The Johns Hopkins University
C12N15/1138A61K31/711C12N15/113C12N2310/111C12N2310/113
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Quick Facts
Patent No.
US 9,458,464
App. No.
14/312,152
Granted
Oct 4, 2016
Kind
B2
Abstract

The present invention relates to the field of neurology. More specifically, the present invention provides methods and composition useful for treating neuropathic pain. In a specific embodiment, the present invention provides a recombinant Kcna2 sense fragment. In another embodiment, the present invention provides a method of treating neuropathic pain comprising the step of administering a composition comprising a recombinant Kcna2 sense fragment.

Claims (10)

1. A method for treating neuropathic pain comprising the step of administering to a patient in need thereof a composition comprising a recombinant Kcna2 sense fragment, wherein the recombinant Kcna2 sense fragment comprises SEQ ID NO:6.

2. The method of claim 1 , wherein the composition further comprises a pharmaceutically acceptable carrier.

3. The method of claim 1 , wherein the patient is human.

4. The method of claim 1 , wherein the composition is administered to the dorsal root ganglion or to the spinal cord of the patient.

5. The method of claim 1 , wherein the composition is administered parenterally.

6. A method for treating neuropathic pain comprising the step of administering to a patient in need thereof a composition comprising a recombinant vector encoding a Kcna2 sense fragment shown in SEQ ID NO:6.

7. The method of claim 6 , wherein the composition further comprises a pharmaceutically acceptable carrier.

8. The method of claim 6 , wherein the patient is human.

9. The method of claim 6 , wherein the composition is administered to the dorsal root ganglion or to the spinal cord of the patient.

10. The method of claim 6 , wherein the composition is administered parenterally.

Assignments (2)
CONFIRMATORY LICENSE Recorded Mar 24, 2017
From: JOHNS HOPKINS UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 042086/0877 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 28, 2016
From: TAO, YUANXIANG
To: JOHNS HOPKINS UNIVERSITY
Reel/Frame 039023/0969 →
Continuity (1)
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