IP Library Granted Patent US 9,468,753
Granted Patent B2
US 9,468,753 · App. 13/918,440 · Granted Oct 18, 2016

System and method for stimulating motor units

Inventors: Lee Fisher (Pittsburg, OH); Ronald Triolo (Cleveland Heights, OH); Dustin J. Tyler (Highland Heights, OH)
Assignee: Case Western Reserve University
A61N1/0556A61N1/36003
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Quick Facts
Patent No.
US 9,468,753
App. No.
13/918,440
Granted
Oct 18, 2016
Kind
B2
Abstract

Systems and methods are provided for stimulating motor units. An electrode array includes a plurality of electrodes configured to provide stimulation to respective motor units of a plurality of independent, mutually agonist motor units. A stimulator assembly is configured to provide a stimulation current to each electrode of the plurality of electrodes. The stimulation current is provided such that a sum of respective time-varying moments at the plurality of motor units remains substantially constant and non-zero.

Claims (15)

1. A system comprising:

an implantable electrode, comprising a number (N) of independently-controlled contacts configured to be arranged so that each contact stimulates a respective nerve of a motor unit, wherein N is a positive integer greater than two; and

a stimulator assembly configured to provide a stimulation current, comprising N waveforms, each varying sinusoidally at a common frequency and shifted in phase by 2π/N relative to the other waveforms, to the electrode, wherein the N waveforms are provided to the N contacts over time to intermittently activate one or more motor units to ensure that a sum of respective responses of muscle fibers of the motor units remains substantially constant and non-zero without diminishing the responses.

2. The system of claim 1 , wherein the electrode comprises three contacts (N=3) and the phase shift between stimulation currents delivered to each contact is (2pi)/3 radians.

3. The system of claim 1 , wherein the stimulator assembly is configured to determine appropriate stimulation currents for the N contacts according to a model representing recruitment and overlap characteristics of the nerves associated with the motor units.

4. The system of claim 1 , wherein a peak output associated with the responses of the muscle fibers of the motor units is less than the non-zero sum.

5. The system of claim 4 , wherein the peak output associated with the responses of the muscle fibers of the motor units is less than three-quarters of the non-zero sum.

6. The system of claim 1 , wherein the stimulator assembly is configured to be implanted within the living body.

7. The system of claim 6 , further comprising a system control configured to communicate with the stimulator assembly and the electrode contacts to adjust the frequency, amplitude, and pulse duration associated with the stimulation current.

8. A system comprising:

an implantable electrode, comprising N electrode contacts, where N is a positive integer greater than two, each configured to be arranged so that each electrode contact activates a nerve of a motor unit; and

a stimulator assembly configured to provide a set of N electrical waveforms, each varying sinusoidally at a common frequency and shifted in phase by 2 π/N relative to the other electrical waveforms, to the N electrode contacts to activate at least two nerves of at least two motor units intermittently, wherein the set of electrical waveforms is configured based on a stimulation parameter determined based on a maximization of a desired response associated with muscle fibers of the motor units and a minimization of an overlap between the N contacts.

9. The system of claim 8 , wherein N is equal to three.

10. The system of claim 8 , wherein the stimulator assembly is configured to be implantable within a living body.

11. The system of claim 10 , further comprising a system control configured to communicate with the stimulator to adjust one of a stimulus amplitude, a pulse duration, and a frequency of the set of electrical waveforms.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 2, 2013
From: FISHER, LEE; TRIOLO, RONALD J.; TYLER, DUSTIN J.
To: CASE WESTERN RESERVE UNIVERSITY
Reel/Frame 031326/0887 →
Continuity (2)
Provisional Application 61659508 · Jun 14, 2012
Related Publication 20140031910A1 · Jan 30, 2014