IP Library Granted Patent US 9,469,637
Granted Patent B2
US 9,469,637 · App. 14/397,066 · Granted Oct 18, 2016

Nitrogenated heterocyclic compound

Inventors: Satoshi Mikami (Kanagawa, JP); Shinji Nakamura (Kanagawa, JP); Tomoko Ashizawa (New York, NY); Shigekazu Sasaki (Kanagawa, JP); Takahiko Taniguchi (Kanagawa, JP); Izumi Nomura (Kanagawa, JP); Masanori Kawasaki (New York, NY)
Assignee: Takeda Pharmaceutical Company Limited
C07D471/04C07D519/00
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Quick Facts
Patent No.
US 9,469,637
App. No.
14/397,066
Granted
Oct 18, 2016
Kind
B2
Abstract

The present invention provides a compound having a PDE2A selective inhibitory action, which is useful as an agent for the prophylaxis or treatment of schizophrenia, Alzheimer's disease and the like. The present invention is a compound represented by the formula (1): wherein each symbol is as described in the specification, or a salt thereof.

Claims (3)

1. A compound which is:

N-((1S)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide or a salt thereof.

2. A pharmaceutical composition comprising an effective amount of N-((1S)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide or a salt thereof, and a pharmaceutically acceptable carrier.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 16, 2014
From: MIKAMI, SATOSHI; NAKAMURA, SHINJI; ASHIZAWA, TOMOKO; SASAKI, SHIGEKAZU; TANIGUCHI, TAKAHIKO; NOMURA, IZUMI; KAWASAKI, MASANORI
To: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Reel/Frame 034520/0253 →
Priority Claims (2)
JP 2012-100374 · Apr 25, 2012 · national
JP 2012-283470 · Dec 26, 2012 · national
Continuity (1)
Related Publication 20150105373A1 · Apr 16, 2015