Compounds and derivatives of 2H-pyrido (3,2-b)(1, 4) oxazin 3)4H)-ones as raf kinase and LRRK2 inhibitors
The present invention provides pharmaceutical compound of formula: wherein A and B are individually an C or N and R1 is an alkyl and R2 is a substituted phenyl, wherein the substituted phenyl comprises 1 to 3 functional groups and R3-R6 are individually a hydrogen, an amine or a halogen disposed in a pharmaceutical carrier.
1. A pharmaceutical composition of formula:
wherein R3, R5, R7, R8, and R10 are independently a hydrogen or a halogen in a pharmaceutical carrier to inhibit raf Kinase, LRRK2 or both.
2. A pharmaceutical composition having the formula:
wherein R3, R5, R7, R8, and R10 are independently a hydrogen or a halogen in a pharmaceutical carrier in an effective amount to inhibit raf Kinase, LRRK2 or both.
3. The pharmaceutical composition of claim 1 , wherein the compound has the formula or the pharmaceutical salts of:
4. A pharmaceutical composition of formula:
in an effective amount to inhibit raf Kinase, LRRK2 or both.