IP Library Granted Patent US 9,511,029
Granted Patent B2
US 9,511,029 · App. 12/562,674 · Granted Dec 6, 2016

Intraorally rapidly disintegrating tablet

Inventors: Tomoya Akutagawa (Iwakuni, JP); Masahiko Narasaki (Iwakuni, JP)
Assignee: Teijin Pharma Limited
A61K9/5026A61K9/0056A61K31/131A61K31/137A61K31/375A61K31/426A61K9/1635
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Quick Facts
Patent No.
US 9,511,029
App. No.
12/562,674
Granted
Dec 6, 2016
Kind
B2
Abstract

The present invention provides an intraorally rapidly disintegrating tablet that can be formed using an ordinary apparatus, that has hardness with no practical problem and that disintegrates rapidly with good feeling in the oral cavity. The present invention is intraorally rapidly disintegrating tablet produced by compression molding of a granule coated with a disintegrant, in which the granule contains a disintegrant also inside thereof and a drug except ambroxol hydrochloride inside and/or outside thereof.

Claims (7)

1. A granule for tablet molding, wherein the granule consists of an inside and a single coating layer: wherein the inside of the granule comprises a disintegrant and the single coating layer consists of a disintegrant,

wherein the disintegrant both in the inside of the granule and in the single coating layer is crospovidone, and the granule contains no drug.

2. The granule according to claim 1 , comprising one or more kinds of pharmaceutically acceptable additives other than a binder in the inside thereof.

3. The granule according to claim 1 , comprising erythritol in the inside thereof.

4. The granule according to claim 1 , comprising mannitol in the inside thereof.

5. The granule according to claim 1 , comprising a void in the inside thereof.

6. The granule according to claim 1 , wherein the single coating layer is applied by powder-coating using water.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2017
From: TEIJIN PHARMA LIMITED
To: TEIJIN LIMITED
Reel/Frame 043931/0102 →
Priority Claims (1)
JP 2005-328722 · Nov 14, 2005 · national
Continuity (2)
Division 12092852
Related Publication 20100009004A1 · Jan 14, 2010