Granted Patent
B2
US 9,539,299 · App. 13/665,597 · Granted Jan 10, 2017
Combination therapy with WT1 peptide vaccine and temozolomide
Inventors:
Haruo Sugiyama (Mino, JP); Toshiki Yoshimine (Ashiya, JP); Akihiro Tsuboi (Osaka, JP); Naoya Hashimoto (Mino, JP)
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Abstract
The present invention relates to combination therapy for cancer with a WT1 peptide vaccine and temozolomide.
Claims (4)
1. A method for treating a WT-1-expressing cancer, comprising administering therapeutically effective doses of a WT1 peptide and temozolomide to a human patient after radiation therapy in need thereof, wherein the WT1 peptide is
2. The method according to claim 1 , wherein the cancer is glioma.
3. The method according to claim 1 , wherein the WT1 peptide and temozolomide are administered to the human patient after extirpative surgery for tumor.
4. The method according to claim 1 , wherein the WT1 peptide and temozolomide are administered to the human patient after a combination therapy of radiation therapy and temozolomide.
Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 31, 2013
From: SUGIYAMA, HARUO; YOSHIMINE, TOSHIKI; TSUBOI, AKIHIRO; HASHIMOTO, NAOYA
To: INTERNATIONAL INSTITUTE OF CANCER IMMUNOLOGY, INC.
Reel/Frame 029729/0082 →
Continuity (2)
Provisional Application
61552209
· Oct 27, 2011