IP Library › Granted Patent US 9,546,196
Granted Patent B2
US 9,546,196 · App. 15/040,228 · Granted Jan 17, 2017

Compositions and methods of treatment of cancers

Inventors: Lirim Shemshedini (Ypsilanti, MI); Shao-Yong Chen (Brookline, MA); Changmeng Cai (Newton, MA); Chen-Lin Hsieh (Brighton, MA)
Assignee: The University of Toledo
C07K7/08A61K31/7048A61K38/06A61K38/07A61K38/08A61K38/10A61K45/06C07K5/081C07K5/1013C07K5/1016C07K5/1019C07K7/06C12N9/88C12Y406/01002A61K38/00
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Quick Facts
Patent No.
US 9,546,196
App. No.
15/040,228
Granted
Jan 17, 2017
Kind
B2
Abstract

Described herein are compositions and methods useful to treat cancers. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.

Claims (5)

1. An isolated peptide, FA4-8R, consisting of the amino acid sequence set forth in [SEQ ID NO: 28], having an OH on the carboxy terminus.

2. A pharmaceutical composition comprising:

the peptide of claim 1 ; and

a pharmaceutically-acceptable carrier.

3. The composition of claim 2 , further comprising a chemotherapeutic agent.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jun 23, 2016
From: UNIVERSITY OF TOLEDO
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 038991/0556 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 25, 2016
From: SHEMSHEDINI, LIRIM; CHEN, SHAO-YONG; CAI, CHANGMENG; HSIEH, CHEN-LIN
To: THE UNIVERSITY OF TOLEDO
Reel/Frame 037825/0842 →
Continuity (4)
Division 14069790 · Nov 1, 2013
Continuation In Part 13375307
Provisional Application 61182712 · May 30, 2009
Related Publication 20160152665A1 · Jun 2, 2016