Foamable sunscreen formulation
The present application relates to sunscreen formulations, including foamable sunscreen formulations, that comprise zinc oxide and titanium dioxide particles, suitably in the size range of about 1-100 nm. The compositions suitably produce a minimal residual whitening effect when applied to a skin surface.
1. A foamable sunscreen formulation comprising:
a) active particles comprising
i) zinc oxide particles having a primary particle size of less than about 100 nm but not less than about 50 nm; and
ii) titanium dioxide particles having a primary particle size of about 100 nm to about 10,000 nm;
b) about 1 wt % microcrystalline cellulose and about 0.2 wt % cellulose gum;
c) about 16 wt % C 12-15 alkyl benzoate, about 1 wt % octyldodecyl neopentanoate, and about 1% wt % butyl octyl salicylate;
d) about 1.2 wt % glyceryl stearate, about 0.5 wt % ceteareth-20, and about 2 wt % polysorbate 80;
e) about 1.8 wt % polyhydroxystearic acid and about 2.7 wt % methyl methacrylate crosspolymer;
f) about 0.8 wt % polyurethane-2, about 0.3 wt % polymethyl methacrylate and about 0.6 wt % tricontanyl PVP film;
g) iron oxide particles comprising red iron oxide particles, yellow iron oxide particles, black iron oxide particles, or mixtures thereof; and
h) about 50 wt % to about 60 wt % water,
wherein the formulation produces a minimal residual whitening effect when applied to a skin surface.
2. The foamable sunscreen formulation of claim 1 , comprising about 0.05 wt % to about 1.0 wt % iron oxide particles having a primary particle size of about 50 nm to about 10 nm.
3. A foamable sunscreen formulation comprising:
a) active particles comprising
i) titanium dioxide particles having a primary particle size of less than about 100 nm but not less than about 50 nm; and
ii) zinc oxide particles having a primary particle size of about 100 nm to about 1 μm;
b) about 1 wt % microcrystalline cellulose and about 0.2 wt % cellulose gum;
c) about 16 wt % C 12-15 alkyl benzoate, about 1 wt % octyldodecyl neopentanoate, and about 1 wt % butyl octyl salicylate;
d) about 1.2 wt % glyceryl stearate, about 0.5 wt % ceteareth-20, and about 2 wt % polysorbate 80;
e) about 1.8 wt % polyhydroxystearic acid and about 2.7 wt % methyl methacrylate crosspolymer;
f) about 0.8 wt % polyurethane-2, about 0.3 wt % polymethyl methacrylate and about 0.6 wt % tricontanyl PVP film;
g) iron oxide particles comprising red iron oxide particles, yellow iron oxide particles, black iron oxide particles, or mixtures thereof; and
h) about 50 wt % to about 60 wt % water,
wherein the formulation produces a minimal residual whitening effect when applied to a skin surface.
4. The foamable sunscreen formulation of claim 3 , comprising about 0.05 wt % to about 1.0 wt % iron oxide particles having a primary particle size of about 50 nm to about 10 nm.
5. A foamable sunscreen formulation comprising:
a) active particles comprising
i) titanium dioxide particles having a primary particle size of less than about 100 nm but not less than about 50 nm; and
ii) zinc oxide particles having a primary particle size of less than 100 nm but not less than 50 nm;
b) about 1 wt % microcrystalline cellulose and about 0.2 wt % cellulose gum;
c) about 16 wt % C 12-15 alkyl benzoate, about 1 wt % octyldodecyl neopentanoate, and about 1 wt % butyl octyl salicylate;
d) about 1.2 wt % glyceryl stearate, about 0.5 wt % ceteareth-20, and about 2 wt % polysorbate 80;
e) about 1.8 wt % polyhydroxystearic acid and about 2.7 wt % methyl methacrylate crosspolymer;
f) about 0.8 wt % polyurethane-2, about 0.3 wt % polymethyl methacrylate and about 0.6 wt % tricontanyl PVP film;
g) iron oxide particles comprising red iron oxide particles, yellow iron oxide particles, black iron oxide particles, or mixtures thereof; and
h) about 50 wt % to about 60 wt % water,
wherein the formulation produces a minimal residual whitening effect when applied to a skin surface.
6. The foamable sunscreen formulation of claim 5 , comprising about 0.05 wt % to about 1.0 wt % iron oxide particles having a primary particle size of about 50 nm to about 10 nm.
7. A method of preventing sun damage to a patient's skin surface, comprising applying the foamable sunscreen formulation of claim 1 to the skin surface.
8. The method of claim 7 , wherein the foamable sunscreen formulation is applied at least once a day.
9. The method of claim 7 , wherein the foamable sunscreen formulation is applied to the arms, face, legs, chest, trunk or hands.
10. A method of preventing sun damage to a patient's skin surface, comprising applying the foamable sunscreen formulation of claim 3 to the skin surface.
11. The method of claim 10 , wherein the foamable sunscreen formulation is applied at least once a day.
12. The method of claim 10 , wherein the foamable sunscreen formulation is applied to the arms, face, legs, chest, trunk or hands.
13. A method of preventing sun damage to a patient's skin surface, comprising applying the foamable sunscreen formulation of claim 5 to the skin surface.
14. The method of claim 13 , wherein the foamable sunscreen formulation is applied at least once a day.
15. The method of claim 13 , wherein the foamable sunscreen formulation is applied to the arms, face, legs, chest, trunk or hands.
16. The foamable sunscreen formulation of claim 1 , wherein the titanium dioxide particles have a primary particle size of about 1100 nm.
17. The foamable sunscreen formulation of claim 3 , wherein the zinc oxide particles have a primary particle size of about 150 nm to about 550 nm.
18. The foamable sunscreen formulation of claim 17 , wherein the zinc oxide particles have a primary particle size of about 380 nm.