Granted Patent
B2
US 9,574,173 · App. 13/296,876 · Granted Feb 21, 2017
Generation of neural stem cells from human trophoblast stem cells
Inventors:
Jau-Nan Lee (Kaohsiung, TW); Tony Tung-Ying Lee (Albuquerque, NM); Yuta Lee (Kaohsiung, TW); Eing-Mei Tsai (Kaohsiung, TW)
Assignee:
ACCELERATED BIOSCIENCES CORP.
View Patent ↗
Loading inventors, assignments & file history…
Abstract
Provided herein are isolated neural stem cells. Also provided are methods for treatment of neurodegenerative diseases using suitable preparations comprising the isolated neural stem cells.
Claims (1)
1. An isolated human neural stem cell produced from an isolated human trophoblastic stem cell, wherein the isolated human neural stem cell expresses Cdx2, Nanog, Ngn3, RARβ, RXRα, RXRβ, RALDH-2, and RALDH-3 proteins, and wherein the isolated human neural stem cell has low levels of expression or an absence of expression of CD33 or CD133 cell surface proteins as compared to the isolated human trophoblastic stem cell.
Assignments (2)
CHANGE OF ADDRESS
Recorded Jun 7, 2017
From: ACCELERATED BIOSCIENCES CORP.
To: ACCELERATED BIOSCIENCES CORP.
Reel/Frame 043279/0971 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 27, 2014
From: LEE, JAU-NAN; LEE, TONY TUNG-YING; LEE, YUTA; TSAI, EING-MEI
To: ACCELERATED BIOSCIENCES CORP.
Reel/Frame 032312/0379 →
Continuity (3)
Provisional Application
61413892
· Nov 15, 2010
Provisional Application
61434790
· Jan 20, 2011