IP Library Granted Patent US 9,623,073
Granted Patent B2
US 9,623,073 · App. 14/935,850 · Granted Apr 18, 2017

Learning motivation improvers

Inventors: Nobuo Tsuruoka (Osaka, JP); Yoshinori Beppu (Osaka, JP); Hirofumi Kouda (Kanagawa, JP); Hiroshi Watanabe (Tokyo, JP)
Assignees: SUNTORY HOLDINGS LIMITED; CEREBOS PACIFIC LIMITED
A61K38/12A23L2/52A23L33/18A61K9/0053A61K31/496A61K31/498A23V2002/00
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Quick Facts
Patent No.
US 9,623,073
App. No.
14/935,850
Granted
Apr 18, 2017
Kind
B2
Abstract

The present invention aims to provide antidepressants which are free from the problem of side effects and are excellent in safety. The present invention also aims to provide learning motivation improvers which are useful for improvement of learning motivation and can be ingested continuously. The present invention provides antidepressants and learning motivation improvers, each comprising a cyclic dipeptide with the 2,5-diketopiperazine structure as an active ingredient.

Claims (11)

1. A method of treating depression comprising administering an effective amount of 2,5-piperazinedione,3,6-bis(phenylmethyl)-,(3S,6S) to a subject in recognized need thereof.

2. The method according to claim 1 , wherein the administration is oral administration.

3. The method according to claim 1 , wherein the 2,5-piperazinedione,3,6-bis(phenylmethyl)-,(3S,6S) is present in a food, beverage, tablet, capsule, powder, granule, solution, or elixir.

4. The method according to claim 1 , wherein the 2,5-piperazinedione,3,6-bis(phenylmethyl)-,(3S,6S) is administered as a prophylactic and/or therapeutic agent for treatment of depression, senile depression symptoms, depressed mood, hypobulia, anxiety, or insomnia or anorexia associated with these symptoms.

5. A method of treating depression comprising administering an antidepressant comprising an effective amount of 2,5-piperazinedione,3,6-bis(phenylmethyl)-,(3S,6S) to a subject in recognized need thereof.

6. The method according to claim 5 , wherein the administration is oral administration.

7. The method according to claim 5 , wherein the antidepressent is present in a food, beverage, tablet, capsule, powder, granule, solution, or elixir.

8. The method according to claim 5 , wherein the antidepressant is administered as a prophylactic and/or therapeutic agent for treatment of depression, senile depression symptoms, depressed mood, hypobulia, anxiety, or insomnia or anorexia associated with these symptoms.

9. A method for improving learning motivation comprising administering an effective amount of 2,5-piperazinedione,3,6-bis(phenylmethyl)-,(3S,6S) to a subject in recognized need thereof.

10. The method according to claim 9 , wherein the administration is oral administration.

11. The method according to claim 9 , wherein the 2,5-piperazinedione,3,6-bis(phenylmethyl)-,(3S,6S) is present in a food, beverage, tablet, capsule, powder, granule, solution, or elixir.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 26, 2019
From: TSURUOKA, NOBUO; BEPPU, YOSHINORI; KOUDA, HIROFUMI; WATANABE, HIROSHI
To: SUNTORY HOLDINGS LIMITED; CEREBOS PACIFIC LIMITED
Reel/Frame 050162/0512 →
MERGER AND CHANGE OF NAME Recorded Aug 26, 2019
From: CEREBOS PACIFIC LIMITED; SUNTORY BEVERAGE & FOOD ASIA PTE. LTD.
To: SUNTORY BEVERAGE & FOOD ASIA PTE. LTD.
Reel/Frame 050243/0923 →
Priority Claims (1)
JP 2009-296164 · Dec 25, 2009 · national
Continuity (3)
Continuation 13965946 · Aug 13, 2013
Continuation 13517109
Related Publication 20160058831A1 · Mar 3, 2016