IP Library › Granted Patent US 9,624,196
Granted Patent B2
US 9,624,196 · App. 15/253,141 · Granted Apr 18, 2017

Inhibitor of p38 MAP kinase

Inventors: Alistair Ian Longshaw (Nottingham, GB); Euan Alexander Fraser Fordyce (Nottingham, GB); Stuart Thomas Onions (Nottingham, GB); John King-Underwood (Pendock, GB); Jennifer Venable (Solana Beach, CA)
Assignees: RESPIVERT LTD.; TOPIVERT PHARMA LTD.
C07D401/12
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Quick Facts
Patent No.
US 9,624,196
App. No.
15/253,141
Granted
Apr 18, 2017
Kind
B2
Abstract

A compound of formula (XV): wherein R 1 represents an amino group, a protected amino group or nitro group; or a salt thereof. The compound is a p38 MAP kinase inhibitor. The compound and its pharmaceutically acceptable salts can be used for treatment of conditions, such as inflammatory diseases.

Claims (11)

1. A compound of formula (XV):

wherein R 1 represents an amino group, a protected amino group or nitro group;

or a salt thereof.

2. A compound of formula (XV) according to claim 1 which is a compound of formula (VIII):

wherein P 1 represents an amine protecting group;

or a salt thereof.

3. A compound according to claim 2 wherein the amine protecting group is t-butyloxycarbonyl.

4. A compound of formula (XV) according to claim 1 which is a compound of formula (III):

or a salt thereof.

5. A compound of formula (XV) according to claim 1 which is a compound of formula (VII):

or a salt thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 20, 2017
From: TOPIVERT PHARMA LIMITED
To: RESPIVERT LIMITED
Reel/Frame 042083/0755 →
Continuity (4)
Continuation 14622368 · Feb 13, 2015
Provisional Application 61940282 · Feb 14, 2014
Provisional Application 61941064 · Feb 18, 2014
Related Publication 20160368896A1 · Dec 22, 2016