Methods for treating IL-6 mediated diseases with antibody molecules specific for IL-6
The invention relates to antibody molecules having specificity for antigenic determinants of IL-6, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
1. A method of treating a human or animal subject suffering from a disorder mediated by IL-6, the method comprising administering to the subject an effective amount of an antibody comprising a heavy chain comprising a sequence comprising SEQ ID NO:16 and a light chain comprising a sequence comprising SEQ ID NO:18.
2. A method of treating a human or animal subject suffering from a disorder mediated by IL-6, the method comprising administering to the subject an effective amount of an antibody comprising a heavy chain comprising a sequence comprising SEQ ID NO:11 and a light chain comprising a sequence comprising SEQ ID NO:13.
3. A method of treating an animal subject suffering from a disorder mediated by IL-6, the method comprising administering to the subject an effective amount of an antibody comprising a heavy chain variable region comprising a sequence comprising SEQ ID NO:2, and a light chain variable region comprising a sequence comprising SEQ ID NO:4.
4. The method of any one of claims 1 - 3 , wherein the disorder is an inflammatory or autoimmune disorder.
5. The method of claim 4 , wherein the disorder is an inflammatory disease.
6. The method of claim 4 , wherein the disorder is rheumatoid arthritis or systemic lupus erythematosus (SLE).
7. The method of claim 4 , wherein the disorder is multiple sclerosis or Guillain-Barr syndrome.