Medical device with intrapore films
The present disclosure relates to a medical device and methods of making the same. The medical device includes a porous substrate and at least one film. The film is formed within the pore of the substrate. The film is intra-porous and does not contact adjacent pores or films.
1. A method of forming a medical device comprising:
depositing a first film-forming composition within a first pore of a substrate;
depositing a second film-forming composition within a second pore of the substrate;
drying the first film-forming composition to form a first intra-pore film disposed within the first pore; and
drying the second film-forming composition to form a second intra-pore film disposed within the second pore, wherein the first intra-pore film and the second intra-pore film are non-contiguous with respect to one another, wherein the first film is formed from a first material having a first degradation rate and the second film is formed from a second material having a second degradation rate different from the first degradation rate.
2. The method according to claim 1 , wherein at least one of depositing of the first film-forming composition or depositing of the second film-forming composition includes solvent casting, molding, spray coating, dip coating, extrusion, or combinations thereof.
3. The method according to claim 1 , wherein the first intra-pore film and the second intra-pore film have an area from about 100 square microns to about 15 square millimeters.
4. The method according to claim 1 , wherein at least one of the first intra-pore film or the second intra-pore film includes at least one therapeutic selected from the group consisting of an analgesic agent, an anesthetic agent, an antibiotic agent, an antimicrobial agent, an anticoagulant agent, a hemostatic agent, and combinations thereof.
5. The method according to claim 1 , wherein the first intra-pore film and the second intra-pore film comprise the same or different materials.
6. The method according to claim 1 , wherein:
depositing a first film-forming composition deposits the first film-forming composition fully within the first pore; and
depositing a second film-forming composition deposits the second film-forming composition fully within the second pore, wherein the second pore is disposed adjacent to the first pore.
7. The method according to claim 1 , wherein the first and second pores are at least in part defined by a yarn that separates the first and second intra-pore films.
8. The method according to claim 1 , wherein an entirety of the first and second intra-pore films are disposed between a first plane defined by a top surface of the substrate and a second plane defined by a bottom surface of the substrate.
9. A method of forming a medical device, comprising:
forming a first film within a first pore of a substrate; and
forming a second film within a second pore of the substrate, the second pore disposed adjacent the first pore of the substrate such that the first film and the second film are non-contiguous with respect to one another, wherein the first film is formed from a first material having a first degradation rate and the second film is formed from a second material having a second degradation rate different from the first degradation rate.
10. The method according to claim 9 , wherein a yarn that is in communication with at least a portion of each of the first and second pores separates the first film and the second film.
11. The method according to claim 9 , wherein an entirety of the first film and the second film are disposed between a first plane defined by a top surface of the substrate and a second plane defined by a bottom surface of the substrate.
12. The method according to claim 9 , wherein the first film and the second film are formed using at least one of solvent casting, molding, spray coating, dip coating, or extrusion.
13. The method according to claim 9 , wherein each of the first film and the second film has an area from about 100 square microns to about 15 square millimeters.
14. The method according to claim 9 , wherein at least one of the first film or the second film includes at least one therapeutic selected from the group consisting of an analgesic agent, an anesthetic agent, an antibiotic agent, an antimicrobial agent, an anticoagulant agent, a hemostatic agent, and combinations thereof.
15. The method according to claim 9 , wherein the first film and the second film are formed from the same or different materials.