Dose measurement system and method
Embodiments described herein generally relate to devices, systems and methods for measuring the dose remaining in a drug delivery device that is used for delivering a dose to a patient. In some embodiments, a dose measurement system for measuring the liquid volume in a container includes a plurality of light sources which are disposed and configured to emit electromagnetic radiation toward the container. A plurality of sensors are located in the apparatus that are optically coupleable to the plurality of light sources and are disposed and configured to detect the electromagnetic radiation emitted by at least a portion of the light sources. The apparatus also includes a processing unit configured to receive data representing the portion of the detected electromagnetic radiation from each of the plurality of sensors. The processing unit is further operable to convert the received data into a signature representative of the electromagnetic radiation detected by the plurality of sensors.
1. An apparatus for measuring liquid volume in a container, the apparatus comprising:
a plurality of light sources disposed and configured to emit electromagnetic radiation toward the container;
a plurality of sensors optically coupleable to the plurality of light sources, each sensor of the plurality of sensors disposed and configured to detect the electromagnetic radiation emitted by at least two of the plurality of light sources;
a processing unit configured to receive data representative of the detected electromagnetic radiation from each of the plurality of sensors, and generate a signal signature representative of the electromagnetic radiation detected by the plurality of sensors; and
a communications module configured to communicate data representative of the signal signature generated by the processing unit between the apparatus and at least one of a user and a remote device.
2. The apparatus of claim 1 , wherein the processing unit is further configured to associate the signal signature with a reference signal signature, the reference signal signature being representative of a liquid volume in the container.
3. The apparatus of claim 1 , wherein the plurality of light sources, the plurality of sensors and the processing unit are disposed in a housing, the housing configured to be removably coupleable to a drug delivery device.
4. The apparatus of claim 3 , wherein the drug delivery device is an injection pen.
5. The apparatus of claim 4 , wherein the housing is a pen cap.
6. The apparatus of claim 5 , wherein at least one of the injection pen and the pen cap includes alignment features configured to allow the pen cap to be coupled to the injection pen in a predetermined radial orientation.
7. The apparatus of claim 1 , wherein the processing unit includes a memory configured to temporarily store at least one of the data representative of the detected electromagnetic radiation from each of the plurality of sensors and the signal signature representative of the electromagnetic radiation detected by the plurality of sensors.
8. The apparatus of claim 1 , wherein the processing unit includes a memory configured to store a plurality of reference signal signatures, each of the plurality of reference signal signatures being representative of a liquid volume in the container.
9. The apparatus of claim 1 , wherein the processing unit includes an RFID chip configured to store information, the RFID chip configured to allow a near field communication-enabled device to read the stored information.
10. The apparatus of claim 1 , wherein the light sources are light emitting diodes.
11. The apparatus of claim 1 , wherein the sensors are photodetectors.
12. The apparatus of claim 1 , wherein the electromagnetic radiation is infrared radiation.
13. The apparatus of claim 1 , wherein the electromagnetic radiation is microwave radiation.
14. The apparatus of claim 1 , wherein the electromagnetic radiation is emitted in pulses.
15. An apparatus, comprising:
a plurality of light sources disposed and configured to emit electromagnetic radiation toward a container;
a plurality of sensors, each sensor of the plurality of sensors disposed and configured to detect the electromagnetic radiation emitted by at least two of the plurality of light sources;
at least one processor configured to receive data representative of the detected electromagnetic radiation from each of the plurality of sensors, and generate a signal signature representative of the electromagnetic radiation detected by the plurality of sensors,
wherein the plurality of light sources and the plurality of sensors are configured to be coupled to a drug delivery device, the drug delivery device having an actuator disposed therein.
16. The apparatus of claim 15 , wherein the at least one processor is further configured to dynamically adapt a drug delivery schedule based on at least the signal signature.
17. The apparatus of claim 15 , wherein the actuator includes a plunger portion.
18. The apparatus of claim 17 , wherein the plunger portion is configured to be in fluid communication with a drug.
19. The apparatus of claim 17 , wherein the at least one processor is further configured to determine a position of the plunger portion based at least in part on a reference signature.
20. The apparatus of claim 17 , wherein the plurality of sensors are configured to obtain reference signal signatures for a plurality of dose volumes.
21. The apparatus of claim 20 , further comprising:
a memory configured to store the reference signal signatures obtained by the plurality of sensors for a plurality of dose volumes.
22. The apparatus of claim 15 , wherein the drug delivery device is configured to communicate a predefined quantity of a drug to a patient.
23. The apparatus of claim 15 , wherein the plurality of light sources and the plurality of sensors are configured to be integrated with the drug delivery device.
24. The apparatus of claim 15 , wherein the apparatus is configured to be coupled to the drug delivery device.
25. The apparatus of claim 15 , wherein the apparatus is configured to be coupled to the drug delivery device of a plurality of sizes.
26. An apparatus, comprising:
a housing defining a bore for receiving at least a portion of a drug delivery device, the drug delivery device including a drug container;
a plurality of light sources disposed in the housing and configured to emit electromagnetic radiation toward the drug container;
a plurality of sensors disposed in the housing, each sensor of the plurality of sensors disposed and configured to detect the electromagnetic radiation emitted by at least two of the plurality of light sources; and
at least one processor configured to receive data representative of the detected electromagnetic radiation from each of the plurality of sensors, and generate a signal signature representative of the electromagnetic radiation detected by the plurality of sensors.
27. The apparatus of claim 26 , wherein the bore is configured to receive at least the portion of the drug delivery device in a predetermined orientation.
28. The apparatus of claim 27 , wherein the predetermined orientation is a radial orientation.
29. The apparatus of claim 26 , wherein the housing includes alignment features for receiving at least the portion of the drug delivery device in a predetermined orientation.
30. The apparatus of claim 29 , wherein the predetermined orientation is a radial orientation.
31. The apparatus of claim 26 , wherein the bore is configured to form a friction fit with the drug delivery device.
32. The apparatus of claim 26 , wherein the bore includes a snap-fit mechanism.
33. The apparatus of claim 32 , wherein the snap-fit mechanism includes at least one of a notch, a groove, a detent, and a thread.