Compositions and methods for treatment of neurodegenerative disease
Compounds, compositions, kits and methods for treating conditions related to neurodegeneration or ocular disease, are disclosed.
1. A method of treating a neurodegenerative disease or disorder, the method comprising administering to a subject in need thereof an effective amount of a pharmaceutical composition consisting essentially of a compound selected from the group consisting of sunitinib, SU11274, SU5416, or SU6656, or a pharmaceutically acceptable salt thereof, thereby treating the neurodegenerative disease or disorder.
2. The method of claim 1 , wherein the neurodegenerative disease or disorder is glaucoma.
3. The method of claim 1 , wherein the glaucoma is not neovascular glaucoma.
4. The method of claim 1 , wherein the subject is a mammal.
5. The method of claim 1 , wherein the subject is a human.
6. The method of claim 1 , further comprising the step of monitoring the subject to determine the efficacy of treatment.
7. The method of claim 1 , wherein the neurodegenerative disease or disorder is wet macular degeneration.
8. The method of claim 1 , wherein the neurodegenerative disease or disorder is dry macular degeneration.