IP Library Granted Patent US 9,700,631
Granted Patent B2
US 9,700,631 · App. 14/238,672 · Granted Jul 11, 2017

Low protein percentage gelling compositions

Inventors: Luke Burnett (Winston-Salem, NC); Elizabeth Kneller (Winston-Salem, NC); Seth Tomblyn (Belmont, NC)
Assignee: KeraNetics, LLC
A61K47/42A61L27/227A61L27/52C08J3/075C08J2300/14C08J2399/00
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Quick Facts
Patent No.
US 9,700,631
App. No.
14/238,672
Granted
Jul 11, 2017
Kind
B2
Abstract

Described herein are low protein concentration gelling compositions comprising keratin proteins.

Claims (21)

1. A hydrogel composition comprising keratose, wherein said hydrogel exhibits a dynamic complex viscosity of at least 113.9 Pascals as measured at 25° Celsius at a frequency of 1 Hertz.

2. The composition of claim 1 , wherein said composition is substantially free of gamma-keratose or gamma-kerateine.

3. The composition of claim 1 , wherein said composition is substantially free of biomaterial adjuncts or crosslinking agents.

4. The composition of claim 1 , wherein said hydrogel is formed between about 25° C. and about 37° C.

5. The composition of claim 1 , wherein said hydrogel is stable at about 25° C. to about 37° C.

6. The composition of claim 1 , wherein said hydrogel comprises at least 90% or more keratose.

7. The composition of claim 6 , wherein said hydrogel is substantially free of kerateine.

8. The composition of claim 6 , wherein said hydrogel is substantially free of disulfide bonds.

9. The composition of claim 1 , wherein said keratose is derived from a human keratin source.

10. The composition of claim 9 , wherein said human keratin source is hair.

11. The composition of claim 1 , wherein said hydrogel exhibits a dynamic complex modulus of at least 811.0 Pa as measured at 25° Celsius at a frequency of 1 Hertz.

12. The composition of claim 1 , wherein said hydrogel exhibits a dynamic elastic/storage modulus of at least 801.9 Pa as measured at 25° Celsius at a frequency of 1 Hertz.

13. The composition of claim 1 , wherein said hydrogel exhibits a dynamic viscous/loss modulus of at least 119.0 Pa as measured at 25° Celsius at a frequency of 1 Hertz.

14. The composition of claim 1 , wherein said hydrogel comprises keratose at a concentration of about 20% or less.

15. The composition of claim 1 , wherein said hydrogel comprises keratose at a concentration of about 15% or more.

16. The composition of claim 11 , wherein said hydrogel comprises keratose at a concentration of about 20% or less.

17. The composition of claim 11 , wherein said hydrogel comprises keratose at a concentration of about 15% or more.

18. The composition of claim 12 , wherein said hydrogel comprises keratose at a concentration of about 20% or less.

19. The composition of claim 12 , wherein said hydrogel comprises keratose at a concentration of about 15% or more.

20. The composition of claim 13 , wherein said hydrogel comprises keratose at a concentration of about 20% or less.

21. The composition of claim 14 , wherein said hydrogel comprises keratose at a concentration of about 15% or more.

Assignments (5)
CHANGE OF NAME Recorded Sep 16, 2019
From: KERATIN BIOSCIENCES INC.
To: KERANETICS, INC
Reel/Frame 050383/0577 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 10, 2019
From: KERANETICS LLC
To: KERATIN BIOSCIENCES, INC.
Reel/Frame 048845/0027 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 3, 2017
From: BURNETT, LUKE
To: KERANETICS, LLC
Reel/Frame 044024/0920 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 3, 2017
From: TOMBLYN, SETH
To: KERANETICS, LLC
Reel/Frame 044024/0949 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 3, 2017
From: KNELLER, ELIZABETH
To: KERANETICS, LLC
Reel/Frame 044025/0009 →
Continuity (2)
Provisional Application 61524549 · Aug 17, 2011
Related Publication 20150011659A1 · Jan 8, 2015