Antioxidant compositions and methods of using the same

1. An antioxidant composition comprising at least one topically acceptable silicone oil in combination with an effective amount of Vitamin C, Vitamin E, and one or more polyphenol antioxidants.

2. The antioxidant composition of claim 1 , wherein the composition further comprises at least one additional antioxidant.

3. The antioxidant composition of claim 2 , wherein the at least one additional antioxidant is creatine.

4. The antioxidant composition of claim 1 , wherein the composition further comprises at least one low molecular weight chromane or chromene derivative with antioxidant properties.

5. The antioxidant composition of claim 3 , wherein the composition further comprises at least one low molecular weight chromane or chromene derivative with antioxidant properties.

6. The antioxidant composition of claim 1 , wherein Vitamin C is present in an amount between 1 and 30%.

7. The antioxidant composition of claim 1 , wherein Vitamin E is present in an amount between 0.1 and 5%.

8. The antioxidant composition of claim 3 , wherein creatine is present in an amount between 0.1 and 5%.

9. The antioxidant composition of claim 4 , wherein the at least one low molecular weight chromane or chromene derivative with antioxidant properties is dimethylmethoxy chromanol.

10. The antioxidant composition of claim 5 , wherein the at least one low molecular weight chromane or chromene derivative with antioxidant properties is dimethylmethoxy chromanol.

11. The antioxidant composition of claim 9 , wherein the dimethylmethoxy chromanol is present in an amount between 0.01 and 1%.

12. The antioxidant composition of claim 10 , wherein the dimethylmethoxy chromanol is present in an amount between 0.01 and 1%.

13. The antioxidant composition of claim 1 , wherein the silicone oil is cyclopentasiloxane or a combination of cyclopentasiloxane and polysilicone-11.

14. The antioxidant composition of claim 1 , wherein the one or more polyphenol antioxidants is selected from the group consisting of flavonoids; flavonols; flavones; catechins; flavanones; anthocyanidins; isoflavonoids; extracts from green tree extracts, milk thistle, soybeans, wine grapes and their seeds, acai berry, coffee berry, feverfew, pomegranate, tropical ferns, and turmeric; and any combinations thereof.

15. The antioxidant composition of claim 14 , wherein the polyphenol antioxidant is epigallocatechin gallate (EGCG).

16. The antioxidant composition of claim 15 , wherein the epigallocatechin gallate (EGCG) is present in an amount between 0.01 and 0.5%.

17. The antioxidant composition of claim 1 , wherein Vitamin C is present in an amount between 1 and 30%, Vitamin E is present in an amount between 0.1 and 5%, and the one or more polyphenol antioxidants is epigallocatechin gallate (EGCG) present in an amount between 0.01 and 0.5%.

18. The antioxidant composition of claim 17 , wherein the composition further comprises a low molecular weight chromane or chromene derivative with antioxidant properties, wherein the low molecular weight chromane or chromene derivative with antioxidant properties is dimethylmethoxy chromanol present in an amount between 0.01 and 0.5%.

19. The antioxidant composition of claim 18 , wherein the composition further comprises creatine present in an amount between 0.1 and 5%.

20. The antioxidant composition of claim 17 , wherein the composition further comprises creatine present in an amount between 0.1 and 5%.

21. The antioxidant composition of claim 1 , wherein the composition further comprises one or more carriers or excipients suitable for topical administration or subcutaneous administration.

22. The antioxidant composition of claim 1 , wherein the Vitamin C is micronized Vitamin C.

23. The antioxidant composition of claim 1 , wherein the composition is substantially free of water.

24. The composition of claim 1 , wherein the composition further comprises one or more additional active ingredients.

25. A pharmaceutical composition comprising the composition of claim 1 and one or more pharmaceutically acceptable carriers.

26. A cosmetic composition comprising the composition of claim 1 and one or more cosmetically acceptable carriers.

27. A kit comprising, in one or more containers, the pharmaceutical composition of claim 25 and instructions for use.

28. A kit comprising, in one or more containers, the cosmetic composition of claim 26 and instructions for use.

29. A method of treating, alleviating, or ameliorating a symptom, condition, disorder, or disease associated with free radicals, the method comprising administering an effective amount of the composition of claim 1 to a patient in need thereof.

30. The method of claim 29 , wherein the symptom, condition, disorder, or disease associated with free radicals is selected from the group consisting of sun induced skin damages, skin aging, skin inflammatory diseases or disorders, skin degenerative diseases or disorders, and cancer.

31. The method of claim 29 , wherein treating, alleviating, or ameliorating the symptom neutralizes free radicals.

32. The method of claim 29 , wherein the method comprises the repeated topical administration of the composition to the patient.

33. The method of claim 32 , wherein the composition is administered to the patient at least once or twice a day for at least 30 days.

34. The method of claim 29 , wherein the method comprises the repeated subcutaneous administration of the composition to the patient.

35. The method of claim 34 , wherein the composition is administered to the patient at least once or twice a day for at least 30 days.

36. A method for modifying free radical damage to skin by administering an effective amount of the composition of claim 1 to the skin of a patient.

37. The method of claim 36 , wherein the effective amount is sufficient to treat, prevent, or treat and prevent free radical damage to the skin.