Compositions and methods for improving human health and nutrition

1. A composition comprising a mixture comprising:

a. a prebiotic,

b. a probiotic comprising a mixture of Pediococcus acidilactici, Pediococcus pentosaceus , and Lactobacillus plantarum microorganisms produced by submerged liquid fermentation, and

c. a postbiotic derived from the liquid fermentation medium of the Pediococcus acidilactici, Pediococcus pentosaceus , and Lactobacillus plantarum microorganisms, wherein the postbiotic is prepared by:

i. collecting the supernatants from the centrifugation of each of the individual anaerobic fermentations of Pediococcus acidilactici, Pediococcus pentosaceus , and Lactobacillus plantarum;

ii. mixing the supernatants together;

iii. freeze-drying the mixed supernatants to a moisture content less than about 5% by weight; and

iv. grinding the dried supernatants of step (iii) to a mean particle size of 295 microns, with 60% of the mixture in the size range between 175-900 microns.

2. The composition of claim 1 wherein the prebiotic is selected from the group consisting of inulin, fructo-oligosaccharides, and gluco-oligosaccharides.

3. The composition of claim 1 , wherein the prebiotic, probiotic, and postbiotic components are combined in equal weight proportion.

4. The composition of claim 1 , formulated into a chewable food, skin cream, lotion, gel or ointment.

5. A formulation comprising the composition of claim 1 , wherein the formulation comprises a vitamin, a mineral, a sugar, a botanical, or a fungal component.

6. The formulation of claim 5 , wherein the vitamin is vitamin A, vitamin B1, B2, B3, B5, B6, B7, B9, B12, vitamin C, vitamin D, vitamin E or vitamin K.

7. The formulation of claim 5 , wherein the mineral is calcium carbonate, calcium lactate, calcium chloride, calcium phosphate (dibasic), sodium chloride, potassium citrate monohydrate, potassium sulfate, potassium phosphate monobasic, magnesium oxide, manganese carbonate, manganese glucanate, ferric citrate, zinc carbonate, zinc glucanate, cupric carbonate, potassium iodate, sodium selenite pentahydrate, chromium potassium sulfate dodecahydrate, ammonium paramolybdate tetrahydrate, sodium meta-silicate nonahydrate, lithium chloride, boric acid, sodium fluoride, nickel carbonate hydroxide tetrahydrate, or ammonium meta-vanadate.

8. The formulation of claim 5 , wherein the sugar is dextrose, sucrose, fructose, inulin, trehalose or salts of gluconic acid.

9. The formulation of claim 5 , wherein the botanical is rhodiola rosea extract, aloe barbedensis, yucca schidigera , aloe vera, boswellia extract, acacia catechu, scutellaria baicalensis , moringa or turmeric.

10. The formulation of claim 5 , wherein the fungal component is gandoderma lucidium, lentinus edodes, hericium erinaceous, agaricus blazei, cordyceps sinensis, grifola frondosa, coriolus veriscolor, coprinus comatus , or grifola frondosa.

11. A method of improving human health comprising administering to the subject the composition of claim 1 .

12. The method of claim 11 , wherein the composition is administered orally.

13. The method of claim 11 , wherein the composition is administered as a tablet, capsule, powder, or granulate.

14. The method of claim 13 , wherein each tablet, capsule, powder, or granulate contains between about 100-800 milligrams.

15. The method of claim 14 , wherein the composition is administered topically.

16. The method of claim 11 , wherein the composition is a liquid, cream, lotion, dispersion, gel or ointment.

17. The method of claim 11 , wherein the composition is present at between 0.1-10% by weight.

18. A method for treating a digestive disorder comprising orally administering the composition of claim 1 .

19. The method of claim 18 , wherein the digestive disorder is constipation, diarrhea dysbiosis, Crohn's disease, food allergy, lactose intolerance pouchitis or ulcerative colitis.

20. A method for reducing comorbidities associated with Metabolic Syndrome X comprising orally administering the composition of claim 1 .

21. A method for treating a skin disorder comprising topically administering the composition of claim 4 .

22. A method of claim 21 , wherein the skin disorder is rosacea, acne, psoriasis, eczema or dermatitis.

23. A method for improving wound healing comprising administering to the wound the composition of claim 4 .

24. The composition of claim 1 , further comprising magnesium stearate.