Oxygen-absorbing resin composition and oxygen-absorbing multilayer body using same, and molded article and medical container using these
Provided is a novel oxygen-absorbing resin composition having excellent oxygen-absorbing performance and suppressing odor generation after absorption of oxygen even if a material responsive to a metal detector is not used. Further provided is an oxygen-absorbing resin composition having excellent oxygen-absorbing performance in a wide range of humidity conditions from low humidity to high humidity. Such an oxygen-absorbing resin composition contains a copolymerized polyolefin compound and a transition metal catalyst, in which the copolymerized polyolefin compound contains at least one constituent unit having a tetralin ring.
1. An oxygen-absorbing resin composition comprising a copolymerized compound and a transition metal catalyst, wherein the copolymerized compound comprises at least one constituent unit (a) selected from the group consisting of the constituent units represented by the following formulas (4) and (5):
and, at least one constituent unit (b) having a tetralin ring, selected from the group consisting of the constituent units represented by the following formulas (2) and (3):
where R 5 , R 6 and R 7 each independently represent a hydrogen atom or a second monovalent substituent, R 8 , R 9 , R 10 and R 11 each independently represent a third monovalent substituent, where the second monovalent substituent and the third monovalent substituent each independently represent at least one selected from the group consisting of a halogen atom, an alkyl group, an alkenyl group, an alkynyl group, an aryl group, a heterocyclic group, a cyano group, a hydroxy group, a carboxyl group, an ester group, an amido group, a nitro group, an alkoxy group, an aryloxy group, an acyl group, an amino group, a mercapto group, an alkylthio group, an arylthio group, a heterocyclic thio group and an imido group, these of which may further have a substituent; if a plurality of R 8 , R 9 , R 10 or R 11 are present, the plurality of R 8 , R 9 , R 10 and R 11 may be the same or different; m represents an integer of 0 to 3, n represents an integer of 0 to 7, p represents an integer of 0 to 6 and q represents an integer of 0 to 4; at least one hydrogen atom is bound to a benzyl position of the tetralin ring; X represents a bivalent group selected from the group consisting of —(C═O)O—, —(C═O)NH—, —O(C═O)—, —NH(C═O)—and —(CHR)s- where s represents an integer of 0 to 12; Y represents —(CHR)t- where t represents an integer of 0 to 12; and R represents a monovalent chemical species selected from the group consisting of a hydrogen atom, a methyl group and an ethyl group.
2. The oxygen-absorbing resin composition according to claim 1 , wherein the transition metal catalyst comprises at least one transition metal selected from the group consisting of manganese, iron, cobalt, nickel and copper.
3. The oxygen-absorbing resin composition according to claim 1 , wherein the transition metal catalyst is contained in an amount of 0.001 to 10 parts by mass in terms of a transition metal based on 100 parts by mass of the copolymerized compound.
4. The oxygen-absorbing resin composition according to claim 1 , wherein a ratio of a content of the constituent unit (a) to a content of the constituent unit (b) contained in the copolymerized compound is 1/99 to 99/1 by molar ratio.
5. The oxygen-absorbing resin composition according to claim 1 , wherein the constituent unit (b) is at least one constituent unit selected from the group consisting of the constituent units represented by the following formulas (6) and (7):
6. An oxygen-absorbing multilayer body comprising at least three layers comprising a sealant layer comprising a thermoplastic resin, an oxygen-absorbing layer comprising the oxygen-absorbing resin composition according to claim 1 , and a gas barrier layer comprising a gas barrier substance, laminated in this order.
7. An oxygen-absorbing multilayer container comprising the oxygen-absorbing multilayer body according to claim 6 .
8. An oxygen-absorbing multilayer container obtained by thermoforming of an oxygen-absorbing multilayer body comprising at least three layers comprising an oxygen transmission layer comprising a thermoplastic resin, an oxygen-absorbing layer comprising the oxygen-absorbing resin composition according to claim 1 and a gas barrier layer comprising a gas barrier substance, laminated in this order, such that the oxygen transmission layer faces inside.
9. An oxygen-absorbing sealed container comprising a cover material comprising the oxygen-absorbing multilayer body according to claim 6 and a gas barrier molded container comprising at least three layers comprising an inner layer comprising a thermoplastic resin, a gas barrier layer comprising a gas barrier substance and an outer layer comprising a thermoplastic resin, laminated in this order, wherein the sealant layer of the cover material and the inner layer of the gas barrier molded container are bonded.
10. An oxygen-absorbing paper container obtained by forming a carton from an oxygen-absorbing multilayer body comprising at least four layers comprising an isolation layer comprising a thermoplastic resin, an oxygen-absorbing layer comprising the oxygen-absorbing resin composition according to claim 1 , a gas barrier layer comprising a gas barrier substance and a paper substrate layer, laminated in this order.
11. A tubular container comprising an oxygen-absorbing multilayer body comprising at least three layers comprising an inner layer comprising a thermoplastic resin, an oxygen-absorbing layer comprising the oxygen-absorbing resin composition according to claim 1 and a gas barrier layer comprising a gas barrier substance, laminated in this order.
12. An oxygen-absorbing medical multilayer molded container comprising at least three layers comprising a first resin layer at least comprising a polyester, an oxygen-absorbing layer comprising the oxygen-absorbing resin composition according to claim 1 and a second resin layer at least comprising a polyester, laminated in this order.
13. An oxygen-absorbing prefilled syringe made capable of storing a medicinal agent in advance in a sealed condition, and releasing the sealed condition to eject the medical agent at the time of use, wherein the prefilled syringe comprises a multilayered structure having at least three layers comprising a first resin layer comprising at least a polyester, an oxygen-absorbing layer comprising the oxygen-absorbing resin composition according to claim 1 , and a second resin layer comprising at least a polyester, in this order.
14. A method for storing a biopharmaceutical, comprising storing the biopharmaceutical in the oxygen-absorbing medical multilayer molded container according to claim 12 .
15. A method for storing a container filled with a drug solution, comprising storing the container filled with a drug solution in an oxygen-absorbing container using the oxygen-absorbing multilayer body according to claim 6 in whole or in part.
16. A method for storing a patch containing a medicinal ingredient, comprising storing the patch containing a medicinal ingredient in an oxygen-absorbing container using the oxygen-absorbing multilayer body according to claim 6 in whole or in part.
17. An oxygen-absorbing PTP packaging body, comprising an oxygen-absorbing bottom material formed of the oxygen-absorbing multilayer body according to claim 6 and a gas barrier cover material composing at least two layers comprising an inner layer comprising a thermoplastic resin and a gas barrier layer comprising a gas barrier substance, layered in this order, wherein the sealant layer of the oxygen-absorbing bottom material and the inner layer of the gas barrier cover material are bonded.
18. An oxygen-absorbing multilayer bottle having at least three layers comprising an oxygen transmission layer comprising a thermoplastic resin, an oxygen-absorbing layer comprising the oxygen-absorbing resin composition according to claim 1 and a gas barrier layer comprising a gas barrier substance, laminated in this order from inside.
19. A method for storing fruit pulps, comprising storing the fruit pulps in an oxygen-absorbing container using the oxygen-absorbing multilayer body according to claim 6 in whole or in part.
20. A method for storing an alcohol beverage, comprising storing the alcohol beverage in an oxygen-absorbing container using the oxygen-absorbing multilayer body according to claim 6 in whole or in part.
21. A method for storing liquid-state tea or paste-state tea, comprising storing the liquid-state tea or paste-state tea in an oxygen-absorbing container using the oxygen-absorbing multilayer body according to claim 6 in whole or in part.
22. A method for storing fruit juice and/or vegetable juice, comprising storing the fruit juice and/or vegetable juice in an oxygen-absorbing container using the oxygen-absorbing multilayer body according to claim 6 in whole or in part.
23. A method for storing a dry product, comprising storing the dry product in an oxygen-absorbing container using the oxygen-absorbing multilayer body according to claim 6 in whole or in part.
24. A method for storing a biopharmaceutical, comprising storing the biopharmaceutical in the oxygen asorbing prefilled syringe according to claim 13 .