Release mechanism for hemostasis clip

1. A release mechanism for a medical device, comprising:

a bushing having a proximal end, a distal end and a channel extending therethrough, the bushing comprising first and second arms extending proximally from the distal end, the first and second arms being biased toward a release configuration in which engagement surfaces at distal ends thereof are retracted radially into the channel;

a core pin insertable through the channel, the core pin being configured to apply a radially expansive pressure to move the arms radially outward from the release configuration into a locking configuration; and

a tissue treatment device containing capsule connected to the bushing by engagement between the engagement surfaces of the first and second arms and a retaining surface of the capsule, the retaining surface of the capsule extending at an angle relative to the engagement surfaces selected so that a first portion of a force transmitted along an axis of the bushing to the first and second arms moves the arms radially inward toward the release configuration before a second portion of the force transmitted by the first and second arms to the capsule exceeds a threshold level at which the tissue treatment device in the tissue treatment device containing capsule dislodges from clipped tissue, the threshold level being approximately 0.947N.

2. The release mechanism of claim 1 , wherein the proximal end of the bushing is coupled to a flexible insertion member of the tissue treatment device.

3. The release mechanism of claim 2 , further comprising a control member extending through the flexible insertion member from a proximal end connected to a handle of the tissue gripping device to a distal end connected to the tissue treatment device.

4. The release mechanism of claim 3 , wherein a distal portion of the control member is inserted through an opening extending through the core pin, the core pin being configured so that a width of the core pin is greater than a biased width between the first and second arms.

5. The release mechanism of claim 4 , wherein the core pin is disc-shaped.

6. The release mechanism of claim 4 , wherein the core pin is cone shaped.

7. The release mechanism of claim 1 , wherein the engagements surfaces are configured to engage the retaining surface at an angle greater than 90° and less than 180° .

8. The release mechanism of claim 7 , wherein the angle is between 110° and 115° .

9. The release mechanism of claim 1 , wherein the first and second arms are symmetrically disposed about an outer surface of the bushing.

10. The release mechanism of claim 9 , wherein the first and second arms are separated from one another by 180° .

11. The release mechanism of claim 1 , wherein the first and second arms move radially inward by between 25.4 and 76.2 microns from the locking configuration to the release configuration.

12. The release mechanism of claim 1 , wherein the bushing is cylindrical.

13. The release mechanism of claim 1 , wherein the engagement surfaces of the first and second arms are hook-shaped.

14. The release mechanisms of claim 1 , wherein the threshold level corresponds to at least one of a type of tissue being treated and a mechanical strength of the tissue treatment device.

15. A system for releasing a tissue gripping device, comprising:

a bushing having a proximal end, a distal end and a channel extending therethrough, the bushing comprising first and second arms extending proximally from the distal end, the first and second arms being biased toward a release configuration in which engagement surfaces at distal ends thereof are retracted radially into the channel;

a core pin insertable through the channel, the core pin being configured to apply a radially expansive pressure to move the arms radially outward from the release configuration into a locking configuration;

a control member extending through a flexible insertion member from a proximal end connected to a handle of the tissue gripping device to a distal end connected to the core pin;

a tissue treatment device containing capsule connected to the bushing by engagement between the engagement surfaces of the first and second alms and a retaining surface of the capsule, the retaining surface of the capsule extending at an angle relative to the engagement surfaces selected so that a first portion of a force transmitted along an axis of the bushing to the first and second arms moves the arms radially inward toward the release configuration before a second portion of the force transmitted by the first and second arms to the capsule exceeds a threshold level at which a tissue treatment device in the tissue treatment device containing capsule dislodges from clipped tissue, the threshold level being approximately 0.947N; and

a tissue treatment device comprising a proximal end and a tissue gripping element at a distal end.

16. The system of claim 15 , wherein the engagements surfaces are configured to engage the retaining surface at an angle greater than 90° and less than 180° .

17. The system of claim 15 , wherein the first and second arms move radially inward by between 25.4 and 76.2 microns from the locking configuration to the release configuration.

18. The system of claim 15 , wherein the engagement surfaces of the first and second arms are hook-shaped.

19. The system of claim 15 , wherein the threshold level corresponds to at least one of a type of tissue being treated and a mechanical strength of the tissue treatment device.