IP Library › Granted Patent US 9,754,694
Granted Patent B2
US 9,754,694 · App. 13/576,539 · Granted Sep 5, 2017

Method and device for producing a

Inventors: Arnd Baurichter (Odense, DK); Oliver Heid (Erlangen, DE); Timothy Hughes (Erlangen, DE)
Assignee: SIEMENS AKTIENGESELLSCHAFT
G21G1/10G21G1/001G21G2001/0042
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Quick Facts
Patent No.
US 9,754,694
App. No.
13/576,539
Granted
Sep 5, 2017
Kind
B2
Abstract

A method for producing a reaction product containing 99m TC may include providing 100 Mo-metal targets to be irradiated, irradiating the 100 Mo-metal target with a proton stream having an energy for the induction of a 100 Mo(p, 2n) 99m TC core reaction, heating the 100 Mo-metal target to over 300° C., recovering incurred 99m Tc in a sublimation-extraction process with the aid of oxygen gas which is conducted over the 100 Mo-metal target forming 99m Tc-Technetium oxide. Further, a device for producing the reaction product containing 99m Tc may include a 100 Mo metal target, an acceleration unit for providing a proton stream, which can be directed to the 100 Mo-Metal target, such that a 100 Mo(p, 2n) 99m TC core reaction is induced upon irradiation of the 100 Mo-metal target by the proton stream, a gas supply line for conducting oxygen gas onto the irradiated 100 Mo-metal target to form 99m TC-Technetium oxide, and a gas discharge line to discharge the sublimated 99m TC-Technetium oxide.

Claims (40)

1. A method for producing a reaction product containing 99m Tc, comprising:

providing a 100 Mo-metal target to be irradiated,

accelerating protons with only a single acceleration unit to form a proton beam having an energy suitable for inducing a 100 Mo(p, 2n) 99m Tc nuclear reaction,

irradiating the 100 Mo-metal target with the proton beam having the energy suitable for inducing the 100 Mo(p, 2n) 99m Tc nuclear reaction,

heating the 100 Mo-metal target to a temperature of over 300° C., and

obtaining the 99m Tc made in the 100 Mo-metal target in a sublimation-extraction process with the aid of oxygen gas, which is routed over the 100 Mo-metal target forming 99m Tc-technetium oxide in the process.

2. The method of claim 1 , additionally comprising feeding the obtained 99m Tc-technetium oxide to an alkaline solution to form 99m Tc-pertechnetate.

3. The method of claim 1 , wherein the 100 Mo-metal target is in the form of a film, in the form of a powder, in the form of tubules, in the form of a grid structure, in the form of spheres, or in the form of metal foam.

4. The method of claim 1 , wherein the 100 Mo-metal target is held by a thermally insulating mount.

5. The method of claim 1 , wherein heating of the 100 Mo-metal target is achieved by the irradiation by the proton beam.

6. The method of claim 1 , wherein the heating is achieved by conducting current through the 100 Mo-metal target.

7. The method of claim 1 , wherein the heating is achieved by heating a chamber in which the 100 Mo-metal target is arranged.

8. A device for producing a reaction product containing 99m Tc, comprising:

a 100 Mo-metal target,

a single accelerator unit for accelerating protons, with only the single acceleration unit, to form a proton beam directed at the 100 Mo-metal target to thereby irradiate the 100 Mo-metal target, the proton beam having an energy which is suitable for inducing a 100 Mo(p, 2n) 99m Tc nuclear reaction when the 100 Mo-metal target is irradiated by the proton beam,

wherein the device is configured to heat the 100 Mo-metal target to a temperature of over 300° C., and

a sublimation-extraction system for extracting 99m Tc, including:

a gas supply line for routing oxygen gas onto the irradiated and heated 100 Mo-metal target forming 99m Tc-technetium oxide by sublimation, and

a gas discharge line for extracting the sublimated 99m Tc-technetium oxide.

9. The device of claim 8 , further comprising a liquid chamber with an alkaline solution into which the 99m Tc-technetium oxide is routed for the formation of 99m Tc-pertechnetate.

10. The device of claim 8 , wherein the 100 Mo-metal target is available in the form of a film, in the form of a powder, in the form of tubules, in the form of a grid structure, in the form of spheres or in the form of metal foam.

11. The device of claim 8 , wherein the 100 Mo-metal target is held by a thermally insulating mount.

12. The device of claim 8 , comprising a circuit for conducting current through the 100 Mo-metal target to heat the 100 Mo-metal target to the temperature of over 300° C.

13. The device of claim 8 , wherein the 100 Mo-metal target is arranged in a heatable chamber to heat the 100 Mo-metal target to the temperature of over 300° C.

14. The method of claim 1 , additionally comprising feeding the obtained 99m Tc-technetium oxide to a sodium hydroxide solution.

15. The device of claim 8 , further comprising a liquid chamber with a sodium hydroxide solution into which the 99m Tc-technetium oxide is routed for the formation of 99m Tc-pertechnetate.

16. The method of claim 1 , additionally comprising feeding the obtained 99m Tc-technetium oxide to a salt solution to form 99m Tc-pertechnetate.

17. The device of claim 8 , further comprising a liquid chamber with a salt solution into which the 99m Tc-technetium oxide is routed for the formation of 99m Tc-pertechnetate.

18. A method for producing a reaction product containing 99m Tc, comprising:

providing a 100 Mo-metal target to be irradiated,

accelerating protons in an acceleration unit to form a proton beam,

irradiating the 100 Mo-metal target with the proton beam having an energy suitable for inducing a 100 Mo(p, 2n) 99m Tc nuclear reaction,

heating the 100 Mo-metal target, by the irradiation by the proton beam, to a temperature of over 300° C., and

obtaining the 99m Tc made in the 100 Mo-metal target in a sublimation-extraction process with the aid of oxygen gas, which is routed over the 100 Mo-metal target, heated to the temperature over 300° C., forming 99m Tc-technetium oxide in the process.

19. The method of claim 18 , comprising forming the proton beam with a single acceleration unit.

20. The method of claim 18 , further comprising feeding the formed 99m Tc-technetium oxide to an alkaline solution to form 99m Tc-pertechnetate.

21. The method of claim 18 , further comprising feeding the formed 99m Tc-technetium oxide to a salt solution to form 99m Tc-pertechnetate.

22. The method of claim 18 , wherein the 100 Mo-metal target comprises a film in the form of: a powder, tubules, a grid structure, spheres, or a metal foam.

23. The method of claim 18 , comprising holding the 100 Mo-metal target with a thermally insulating mount.

24. The device of claim 8 , wherein the 100 Mo-metal target is heated to the temperature over 300° C. by the irradiation of the proton beam from the single accelerator unit.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2012
From: BAURICHTER, ARND, DR.; HEID, OLIVER, DR.; HUGHES, TIMOTHY, DR.
To: SIEMENS AKTIENGESELLSCHAFT
Reel/Frame 028945/0994 →
Priority Claims (1)
DE 10 2010 006 434 · Feb 1, 2010 · national
Continuity (1)
Related Publication 20120307954A1 · Dec 6, 2012