IP Library Granted Patent US 9,770,583
Granted Patent B2
US 9,770,583 · App. 14/630,471 · Granted Sep 26, 2017

Polymer formulations for nasolacrimal stimulation

Inventors: Amitava Gupta (Roanake, VA); Marie Dvorak Christ (Laguna Beach, CA); F. Richard Christ (Laguna Beach, CA)
Assignee: Oculeve, Inc.
A61N1/0546A61N1/0456C08F220/54C08F230/08H01B1/125A61N1/0496A61N1/36014Y10T29/49826Y10T29/49885
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Quick Facts
Patent No.
US 9,770,583
App. No.
14/630,471
Granted
Sep 26, 2017
Kind
B2
Abstract

Described herein are polymer formulations for facilitating electrical stimulation of nasal or sinus tissue. The polymer formulations may be hydrogels that are prepared by a UV cross-linking process. The hydrogels may be included as a component of nasal stimulator devices that electrically stimulate the lacrimal gland to improve tear production and treat dry eye. Additionally, devices and methods for manufacturing the nasal stimulators, including shaping of the hydrogel, are described herein.

Claims (7)

1. A hydrogel electrode for electrical stimulation of nasal tissue, wherein the hydrogel electrode is made from a formulation comprising a mixture of:

glycerol monomethacrylate;

trimethylol propane trimethacrylate;

dimethylacrylamide;

N-vinylpyrrolidone;

2,4,6-trimethylbenzoyl-diphenylphosphine oxide; and

methanol.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 21, 2015
From: LOUDIN, JAMES DONALD; GUPTA, AMITAVA; WARDLE, JOHN; STIVERS, CHRISTOPHER WILLIAM; DORAISWAMY, ANAND; CHRIST, MARIE DVORAK; CHRIST, F. RICHARD
To: OCULEVE, INC.
Reel/Frame 035462/0346 →
Continuity (5)
Provisional Application 61944340 · Feb 25, 2014
Provisional Application 62027139 · Jul 21, 2014
Provisional Application 62035221 · Aug 8, 2014
Provisional Application 62067350 · Oct 22, 2014
Related Publication 20150238754A1 · Aug 27, 2015